BDMC-A, an analog of curcumin, inhibits markers of invasion, angiogenesis, and metastasis in breast cancer cells via NF-κB pathway—a comparative study with …

K Mohankumar, S Sridharan, S Pajaniradje… - Biomedicine & …, 2015 - Elsevier
Breast cancer chemoprevention has become increasingly important in India as it faces a
potential breast cancer epidemic over the next decade. Curcumin, the active ingredient in …

Synthetic curcumin analog: Inhibiting the invasion, angiogenesis, and metastasis in human laryngeal carcinoma cells via NF-kB pathway

K Mohankumar, AP Francis, S Pajaniradje… - Molecular Biology …, 2021 - Springer
Background Laryngeal carcinoma, the most common among head and neck squamous cell
carcinoma (HNSCC), induces 1% of all cancer deaths. Curcumin the active constituent of …

Dissecting the role of curcumin in tumour growth and angiogenesis in mouse model of human breast cancer

S Bimonte, A Barbieri, G Palma, D Rea… - BioMed research …, 2015 - Wiley Online Library
Breast cancer is considered the most common cancer for women worldwide and it is now the
second leading cause of cancer‐related deaths among females in the world. Since breast …

Curcumin inhibits metastatic progression of breast cancer cell through suppression of urokinase-type plasminogen activator by NF-kappa B signaling pathways

H Zong, F Wang, Q Fan, L Wang - Molecular biology reports, 2012 - Springer
Abstract Curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione), is
extracted from the plant Curcuma longa. It was recently reported for its anticancer effect on …

Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFκB, cyclinD and MMP-1 transcription

Q Liu, WTY Loo, SCW Sze, Y Tong - Phytomedicine, 2009 - Elsevier
Curcumin, an active constituent of turmeric, has been shown to possess inhibitory effect of
cell proliferation and induction of apoptosis towards a board range of tumors. Cell inhibition …

Curcumin inhibits MCF‑7 cells by modulating the NF‑κB signaling pathway

JL Liu, YY Pan, O Chen, Y Luan, X Xue… - Oncology …, 2017 - spandidos-publications.com
The present study investigated the inhibitory effect of curcumin on human breast cancer
MCF‑7 cells and investigated the potential underlying molecular mechanisms. MCF‑7 cells …

[HTML][HTML] The target differences of anti-tumorigenesis potential of curcumin and its analogues against HER-2 positive and triple-negative breast cancer cells

E Meiyanto, U Husnaa, RF Kastian… - Advanced …, 2020 - pmc.ncbi.nlm.nih.gov
Purpose: The current study aims to evaluate the in vitro cytotoxic and cell migration effects of
synthetic curcumin and its analogues on HER2 and nuclear factor kappa B (NFκB) …

Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-κBp65 expression in breast cancer MDA-MB-231 cells

TL Chiu, CC Su - International journal of molecular …, 2009 - spandidos-publications.com
Curcumin (1, 7-bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione), is extracted
from the plant Curcuma longa. It has cytotoxic effects and induces apoptosis in many human …

Curcumin: the spicy modulator of breast carcinogenesis

U Banik, S Parasuraman, AK Adhikary… - Journal of Experimental & …, 2017 - Springer
Worldwide breast cancer is the most common cancer in women. For many years clinicians
and the researchers are examining and exploring various therapeutic modalities for breast …

Curcumol suppresses breast cancer cell metastasis by inhibiting MMP-9 via JNK1/2 and Akt-dependent NF-κB signaling pathways

L Ning, H Ma, Z Jiang, L Chen, L Li… - Integrative cancer …, 2016 - journals.sagepub.com
Curcumolhas been reported to possess antitumor activity. However, its effect and
mechanisms against tumor metastasis are still unclear. This study is to investigate the …