Surface-enhanced Raman scattering (SERS) spectroscopy for sensing and characterization of exosomes in cancer diagnosis

L Guerrini, E Garcia-Rico, A O'Loghlen, V Giannini… - Cancers, 2021 - mdpi.com
Simple Summary The distinct molecular and biological properties of exosomes, together
with their abundance and stability, make them an ideal target in liquid biopsies for early …

[HTML][HTML] Exosome detection via surface-enhanced Raman spectroscopy for cancer diagnosis

J Li, Y Li, P Li, Y Zhang, L Du, Y Wang, C Zhang… - Acta biomaterialia, 2022 - Elsevier
As nanoscale extracellular vesicles, exosomes are secreted by various cell types, and they
are widely distributed in multiple biological fluids. Studies have shown that tumor-derived …

Identification and analysis of exosomes by surface-enhanced Raman spectroscopy

A Merdalimova, V Chernyshev, D Nozdriukhin… - Applied Sciences, 2019 - mdpi.com
The concept of liquid biopsy has emerged as a novel approach for cancer screening, which
is based on the analysis of circulating cancer biomarkers in body fluids. Among the various …

Label-free exosomal detection and classification in rapid discriminating different cancer types based on specific Raman phenotypes and multivariate statistical …

P Zhang, L Wang, Y Fang, D Zheng, T Lin, H Wang - Molecules, 2019 - mdpi.com
Exosomes contain different functional bimolecular characteristics related to physiological or
pathological processes and are now recognized as new biomarkers in different human …

Recent advances in nanomaterial-based biosensors for the detection of exosomes

L Zhang, C Gu, J Wen, G Liu, H Liu, L Li - Analytical and Bioanalytical …, 2021 - Springer
Exosomes are a type of extracellular vesicle actively secreted by almost all eukaryotic cells.
They are ideal candidates for reliable next-generation biomarkers in the early diagnosis and …

Highly sensitive detection of exosomes by SERS using gold nanostar@ Raman reporter@ nanoshell structures modified with a bivalent cholesterol-labeled DNA …

YF Tian, CF Ning, F He, BC Yin, BC Ye - Analyst, 2018 - pubs.rsc.org
Exosomes, as important signal transmitters, play a key role in intercellular communication,
especially in cancer metastasis. There is considerable evidence that exosomes can be used …

Correlation between cancerous exosomes and protein markers based on surface-enhanced Raman spectroscopy (SERS) and principal component analysis (PCA)

H Shin, H Jeong, J Park, S Hong, Y Choi - ACS sensors, 2018 - ACS Publications
Exosomes, which are nanovesicles secreted by cells, are promising biomarkers for cancer
diagnosis and prognosis, based on their specific surface protein compositions. Here, we …

Identification of individual exosome‐like vesicles by surface enhanced raman spectroscopy

S Stremersch, M Marro, BE Pinchasik, P Baatsen… - Small, 2016 - Wiley Online Library
Exosome‐like vesicles (ELVs) are a novel class of biomarkers that are receiving a lot of
attention for the detection of cancer at an early stage. In this study the feasibility of using a …

[HTML][HTML] Molecular detection and analysis of exosomes using surface-enhanced Raman scattering gold nanorods and a miniaturized device

EA Kwizera, R O'Connor, V Vinduska, M Williams… - Theranostics, 2018 - ncbi.nlm.nih.gov
Exosomes are a potential source of cancer biomarkers. Probing tumor-derived exosomes
can offer a potential non-invasive way to diagnose cancer, assess cancer progression, and …

Recent achievements in exosomal biomarkers detection by nanomaterials-based optical biosensors-a review

B Shao, Z Xiao - Analytica chimica acta, 2020 - Elsevier
Exosomal biomarkers including tumor-derived exosomes, exosomal surface proteins and
exosomal nucleic acids have emerged as one of the most important and general cancer …