Studies of the electrophysiologic properties of the single myocardial fibers which contribute
to the understanding of the relation between electrolytes and arrhythmias have been …

NT EW information derived from the electrophysiological laboratory, in particular from
studies employing microelectrodes, has con-tributed to a more rational approach to the …

This section is divided into three parts:(1) a general discussion of the characteristics of the
ionic currents and their relationships to the action potentials of the various types of cardiac …

The actions of pharmacologic agents used in the treatment of cardiac arrhythmias have
been studied extensively in both clinic and laboratory for many years. Introduction of the …

Microelectrode techniques have enabled electrical activity of cardiac fibers to be studied
under physiologic conditions as well as under the influence of a variety of external factors …

While a number of electrolytes play a role in the genesis of the transmembrane action
potential (AP), the changes in the action potential most clearly related to arrhythmias are …

There are several approaches to the prevention and treatment of cardiac arrhythmias. If an
abnormality of rhythm clearly results from operation of a mechanism extrinsic to the heart …

HE EFFECTS OF DIGITALIS on the electrical activity of the heart have been studied
extensively both in the clinic and the laboratory and the major actions of this agent have …

It is well known that changes in serum potassium cause ventricular arrhythmias as a result of
clearly documented changes in the electrophysiological characteristics of single fibers …

Variation in concentration of potassium and calcium ions in the extracellular fluid produce
specific and well defined changes in the shape and duration of the transmembrane action …