Background Serious life-threatening and life-limiting illnesses place an enormous burden on
society and health systems. Understanding how this burden will evolve in the future is …

Background Improving survival and extending the longevity of life for all populations
requires timely, robust evidence on local mortality levels and trends. The Global Burden of …

Background How long one lives, how many years of life are spent in good and poor health,
and how the population's state of health and leading causes of disability change over time …

Background Plausible projections of future mortality and disability are a useful aid in
decisions on priorities for health research, capital investment, and training. Rates and …

Background Regular, detailed reporting on population health by underlying cause of death
is fundamental for public health decision making. Cause-specific estimates of mortality and …

Background Detailed, comprehensive, and timely reporting on population health by
underlying causes of disability and premature death is crucial to understanding and …

Background Non-fatal outcomes of disease and injury increasingly detract from the ability of
the world's population to live in full health, a trend largely attributable to an epidemiological …

Background Up-to-date evidence about levels and trends in disease and injury incidence,
prevalence, and years lived with disability (YLDs) is an essential input into global, regional …

Background Up-to-date evidence about levels and trends in disease and injury incidence,
prevalence, and years lived with disability (YLDs) is an essential input into global, regional …

Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs)
provide summary measures of health across geographies and time that can inform …