The emergence of multiple drug resistant pathogenic bacteria has severely constricted the
antimicrobial options of treating infectious diseases. One of the powerful mechanisms of …

Antimicrobial drug resistance becomes a major challenge in spread of infectious diseases 1.
Efflux pumps are known as transport proteins which have the ability to expel out toxic …

Ever increasing numbers of antibiotic resistances are putting more and more pressure on
research and global health systems. Multidrug-resistant bacteria even escape from second …

The current global antimicrobial resistance (AMR) crisis is a serious hazard to public health,
food security, and development. Drug-resistant pathogens diminish the effectiveness of …

The increasing multi-drug resistance has become a major threat to the public health.
Overexpression of multidrug efflux pumps is one of the major mechanisms of drug resistance …

Efflux mechanisms have become broadly recognized as major components of resistance to
many classes of antibiotics. Some efflux pumps selectively extrude specific antibiotics, while …

The rapid spread of bacteria expressing multidrug resistance (MDR) has necessitated the
discovery of new antibacterials and resistance-modifying agents. Since the initial discovery …

Active efflux of antibiotics is one of the major mechanisms of drug resistance in bacteria. The
efflux process is mediated by membrane transporters with a large variety of unrelated …

Introduction: One of the possibilities for reducing the emergence and spread of antibiotic
resistance is the use of anti-resistance compounds capable of resensitizing resistant …

The potential for the build-up of resistance to a particular antibiotic endangers its therapeutic
application over time. In recent decades, antibiotic resistance has become one of the most …