Introduction: High Grade Prostatic Intraepithelial Neoplasia (HGPIN) was originally thought
to be a cancer precursor, but subsequent data has questioned its prognostic significance …

Because prostate cancer has a long latency and high incidence, it is a good target for
chemoprevention by agents such as retinoids, antiandrogens, antiestrogens, and vitamin D …

673: Men with High-Grade Prostatic Intraepithelial Neoplasia (HGPIN) Remain at High Risk
for Prostate Cancer Regardless of wheth Page 1 184 THE JOURNAL OF UROLOGY® 673 …

Prostatic Intraepithelial Neoplasia (PIN) is an increasingly common finding at ultrasound
guided prostate biopsy, with the high grade form (HGPIN) thought to be" precancerous". With …

High-grade prostatic intraepithelial neoplasia (PIN) is the earliest accepted stage in
carcinogenesis, possessing most of the phenotypic and biochemical changes in cancer …

High-grade prostatic intraepithelial neoplasia is the most likely precursor of prostatic
adenocarcinoma, according to virtually all available evidence. It has a high predictive value …

INTRODUCTION High‐grade prostatic intraepithelial neoplasia (HGPIN) is a recognized
precursor stage of PCa. Men who present HGPIN in a first prostate biopsy face years of …

High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor
to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular …

Objectives: To evaluate the potential application of chemoprevention strategies in prostatic
intraepithelial neoplasia. Methods: Review of relevant literature on chemoprevention with …

A chemoprevention (CP) strategy has evolved for conducting efficient clinical trials for
prostate cancer (PCa) prevention. It integrates five key components, including agents …