The early diagnosis of prostate cancer has been facilitated by the development of serum
prostate-specific antigen (PSA) testing and evolution in transrectal ultrasound-guided biopsy …

Purpose Prostatic intraepithelial neoplasia (PIN) is considered as a precursor lesion for
adenocarcinoma of the prostate. Most data supporting this relationship comes from the short …

In recent years, prostate cancer has become an increasing health problem in North America
and Western Europe, now being the most commonly diagnosed noncutaneous malignancy …

Aims: There is controversy regarding the role of high grade prostatic intraepithelial
neoplasia (HGPIN) on prostatic needle biopsy (PNB) as a risk factor for prostatic …

OBJECTIVE To review specific histological variables in patients with prostate cancer who
previously had diagnoses of high‐grade prostatic intraepithelial neoplasia (HGPIN) and/or …

High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor of
prostate cancer (PCa), according to virtually all available evidence [1]. This lesion is …

PURPOSE: High grade prostatic intraepithelial neoplasia is likely a premalignant lesion of
the prostate. Decreasing the frequency of high grade PIN may decrease the risk of prostate …

Introduction High grade prostatic intraepithelial neoplasia (HGPIN) is regarded as a
precursor of prostate cancer (PC). However, its relationship to cancer has changed …

Objective To investigate if the presence of concomitant high-grade prostatic intraepithelial
neoplasia (HGPIN) or atypical small acinar proliferation (ASAP) on biopsy increases the risk …

Bostwick DG & Cheng L (2012) Histopathology 60, 4–27 Precursors of prostate cancer High‐
grade prostatic intraepithelial neoplasia (PIN) is the only accepted precursor of prostatic …