Sufficient epidemiological investigations demonstrate that there is a close correlation
between obesity and vascular dysfunction. Nevertheless, specific mechanisms underlying …

Objective—Obesity and hypertension are comorbid in epidemic proportion, yet their
biological connection is largely a mystery. The peptide chemerin is a candidate for …

Adipocytes produce adipokines, including chemerin, a chemoattractant that mediates effects
through its ChemR23 receptor. Chemerin has been linked to endothelial dysfunction and …

Chemerin and its G protein-coupled receptor [chemerin receptor 23 (ChemR23)] have been
associated with endothelial dysfunction, inflammation, and insulin resistance. However, the …

Adipose tissue, initially known only for storing excess fat, produces a number of active
cytokine-like hormones, collectively known as adipokines or adipocytokines. These …

Chemerin acting via its distinct G protein-coupled receptor CMKLR1 (ChemR23), is a novel
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …

Atherosclerosis (AS), a chronic arterial disease, is characterized by endothelial dysfunction,
inflammatory reactions and lipid accumulation in parallel with aberrant angiogenesis and …

Background: Obesity-induced hypertension (OIH) has a high morbidity and mortality, and its
prevention and treatment has been a major challenge in clinical practice. Chemerin is a …

Many factors contribute to the development of atherosclerosis. Over the past few years,
understanding of the importance of inflammation during all stages of atherosclerosis …

Plasma levels of chemerin, an adipocytokine produced from the adipose tissues and liver,
are associated with metabolic syndrome and coronary artery disease (CAD). Chemerin and …