Mpox or monkeypox virus (MPXV) belongs to the subclass of Poxviridae and has emerged
recently as a global threat. With a limited number of anti-viral drugs available for this new …

Ion channels of viruses (viroporins) represent a common type of protein targets for drugs.
The relative simplicity of channel architecture allows convenient computational modeling …

The BM2 and NB proteins of Influenza B virus (the B virus) and the CM2 protein of Influenza
C virus (the C virus) are structural homologs of the M2 protein of Influenza A virus (the A …

Viroporins are a group of viral proteins that participate in viral replication cycles, including
modification of membrane permeability and promotion of viral release. Although biological …

Channel-forming proteins are found in a number of viral genomes. In some cases, their role
in the viral life cycle is well understood, in some cases it needs still to be elucidated. A …

[Search for sites containing functionally important substitutions in series of related or mutant
proteins] - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

Influenza is an ancient disease that has infected humans in irregular intervals throughout
recorded history. The most infamous pandemic was “Spanish Flu” which affected large parts …

This review summarizes the types of evidence that can be invoked in order to demonstrate
that a virally encoded protein possesses ion channel activity that is intrinsic to the life cycle …

The channel‐forming trans‐membrane domain of Vpu (Vpu TM) from HIV‐1 is known to
enhance virion release from the infected cells and is a potential target for ion‐channel …

The small hydrophobic (SH) protein is encoded by the human respiratory syncytial virus. Its
absence leads to viral attenuation in the context of whole organisms, and it prevents …