Background The COVID-19 pandemic has led to more than 760,000 deaths worldwide
(correct as of 16th August 2020). Studies suggest a hyperinflammatory response is a major …

Background Inflammatory biomarkers are associated with severity of coronavirus disease
2019 (COVID-19). However, direct comparisons of their utility in COVID-19 versus other …

The COVID-19 pandemic caused by infection with Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) has led to more than 100,000 deaths in the United States …

Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …

Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19) …

Background Prognostic tools are required to guide clinical decision-making in COVID-19.
Methods We studied the relationship between the ratio of interleukin (IL)-6 to IL-10 and …

Several studies have revealed that the hyper-inflammatory response induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major cause of disease …

The objective of the study was to identify distinct patterns in inflammatory immune responses
of COVID-19 patients and to investigate their association with clinical course and outcome …

Inflammatory biomarkers may be associated with disease severity and increased mortality in
COVID-19 patients but have not been studied in North American populations. We sought to …

The severity of COVID-19 is largely determined by the inflammatory response, a “Cytokine
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …