Comparison of the efficacy of sofosbuvir plus ribavirin in Chinese patients with genotype 3a or 3b HCV infection

R Huang, H Rao, Q Xie, Z Gao, W Li… - Journal of Medical …, 2019 - Wiley Online Library
Abstract Background and Aim Genotype 3b hepatitis C virus (HCV) infection represents
approximately 50% of patients with genotype 3 in China. We compared the efficacy of …

Sofosbuvir/velpatasvir fixed-dose combination for the treatment of chronic hepatitis C virus infection.

V Nehra, SA Rizza, Z Temesgen - Drugs of Today (Barcelona, Spain …, 2017 - europepmc.org
The fixed-dose combination of sofosbuvir, a nucleotide analogue NS5B polymerase
inhibitor, and velpatasvir, a second-generation NS5A inhibitor, has been approved by the …

Safety and efficacy of sofosbuvir-velpatasvir to treat chronic hepatitis C virus infection in treatment-naive patients in Rwanda (SHARED-3): a single-arm trial

F Kateera, F Shumbusho, L Manirambona… - The Lancet …, 2022 - thelancet.com
Summary Background Hepatitis C virus (HCV) genotype 4 is the predominant type of HCV
found in sub-Saharan Africa. Various genotype 4 subtypes, such as 4r, frequently have …

Resistance studies of a dithiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems

HM Lin, JC Wang, HS Hu, PS Wu… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Hepatitis C virus (HCV), a member of the Flaviviridae family, affects approximately 3% of the
world's population and is becoming the leading cause of liver disease in the world …

Sofosbuvir with velpatasvir in treatment-naive noncirrhotic patients with genotype 1 to 6 hepatitis C virus infection: a randomized trial

GT Everson, WJ Towner, MN Davis… - Annals of internal …, 2015 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
Supplement. Background: Effective, pangenotypic treatments for hepatitis C virus (HCV) …

Analysis of HCV Resistance Variants in a Phase 3 Trial of Daclatasvir Combined With Asunaprevir for Japanese Patients with Genotype 1 b Infection: 1111

F McPhee, J Toyota, K Chayama, H Miyagoshi… - Hepatology, 2013 - journals.lww.com
Background The all-oral combination of daclatasvir 60mg QD, a first-in-class HCV NS5A
inhibitor with pan-genotypic activity in vitro, and asunaprevir 1 00mg BID, a selective NS3 …

Sofosbuvir–velpatasvir: A single-tablet treatment for hepatitis C infection of all genotypes

MM Miller - American Journal of Health-System Pharmacy, 2017 - academic.oup.com
Purpose The pharmacology, pharmacokinetics, interaction potential, efficacy, and safety of
the newest direct-acting antiviral (DAA) medication for the treatment of chronic hepatitis C …

Sofosbuvir (GS-7977), a pan-genotype, direct-acting antiviral for hepatitis C virus infection

M Rodríguez-Torres - Expert review of anti-infective therapy, 2013 - Taylor & Francis
Given the global importance of chronic hepatitis C virus infection as a major health burden,
there is still a need for treatment options that are more efficient, safer, simpler, more …

[HTML][HTML] 5′ UTR and NS5B-based genotyping of hepatitis C virus in patients from Damietta governorate, Egypt

RR El-Tahan, AM Ghoneim, H Zaghloul - Journal of advanced research, 2018 - Elsevier
Chronic hepatitis C virus (HCV) infection is a main health problem in Egypt causing high
rates of mortalities. Egypt has the highest HCV prevalence in the world, with specific HCV …

Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options

IM Jacobson, SC Gordon, KV Kowdley… - New England journal …, 2013 - Mass Medical Soc
Background Patients chronically infected with hepatitis C virus (HCV) genotype 2 or 3 for
whom treatment with peginterferon is not an option, or who have not had a response to prior …