Aging research has undergone unprecedented advances at an accelerating rate in recent
years, leading to excitement in the field as well as opportunities for imagination and …

Age‐related bone loss is in large part the consequence of senescence mechanisms that
impact bone cell number and function. In recent years, progress has been made in the …

After a long and sometimes painful incubation period, biochemical research on aging has
done what we all do eventually: It's come of age. The goal of the field is a deeper …

The field of aging research has progressed rapidly over the past few decades. Genetic
modulators of aging rate that are conserved over a broad evolutionary distance have now …

Historically, cellular senescence has been viewed as an irreversible cell-cycle arrest
process with distinctive phenotypic alterations that were implicated primarily in aging and …

Why do we age? Scientists have been baffled by this question for centuries and disagree
regarding even the general nature of aging. Is aging the result of fundamental limitations that …

Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for …

The health of an organism is orchestrated by a multitude of molecular and biochemical
networks responsible for ensuring homeostasis within cells and tissues. However, upon …

Through the progress of basic science research, fundamental mechanisms that contribute to
age-related decline are being described with increasing depth and detail. Although these …

Aging is a physiological process mediated by numerous biological and genetic pathways,
which are directly linked to lifespan and are a driving force for all age-related diseases …