HIV-1 reservoirs preclude virus eradication in patients receiving highly active antiretroviral
therapy (HAART). The best characterized reservoir is a small, difficult-to-quantify pool of …

Therapeutic strategies are being clinically tested either to eradicate latent HIV reservoirs or
to achieve virologic control in the absence of antiretroviral therapy. Attaining this goal will …

HIV latency is multifactorial and thus the eradication of HIV infection may require multiple
approaches. Translational efforts employing pharmacological methods to target HIV latency …

Advances in the treatment of HIV infection have dramatically reduced the death rate from
AIDS and improved the quality of life of many HIV-infected individuals. However, the …

HIV infection can persist in spite of efficacious antiretroviral therapies. Although incomplete
inhibition of viral replication may contribute to this phenomenon, this is largely due to the …

Stable remission is the ultimate goal of HIV therapy. A review of recent studies on the ability
of HIV to persist despite highly active antiretroviral therapy (HAART) and immune stimulation …

Combination antiretroviral therapy (cART) can reduce HIV-1 viremia to clinically
undetectable levels. However, replication competent virus persists in a long-lived latent …

Background Identifying where human immunodeficiency virus (HIV) persists in people living
with HIV and receiving antiretroviral therapy is critical to develop cure strategies. We …

HIV-1 infection can now be readily controlled with combination antiretroviral therapy.
However, the virus persists indefinitely in a stable latent reservoir in resting CD4+ T cells …

The apparent cure of an HIV-infected person following hematopoietic stem cell
transplantation (HSCT) from an allogeneic donor homozygous for the ccr5Δ32 mutation has …