Plasma HIV viremia can be suppressed and maintained below the limits of detection for
prolonged periods of time in the vast majority of HIV-infected individuals who receive …

Objectives: Therapies to achieve sustained antiretroviral therapy-free HIV remission will
require validation in analytic treatment interruption (ATI) trials. Identifying biomarkers that …

Background. Some human immunodeficiency virus (HIV)–infected individuals initiating
combination antiretroviral therapy (cART) with low CD4 counts achieve viral suppression but …

Human immunodeficiency virus (HIV) eradication or long-term suppression in the absence
of antiretroviral therapy (ART) requires an understanding of all viral reservoirs that could …

The basis for the extensive variability seen in the reconstitution of CD4+ T cell counts in HIV-
infected individuals receiving highly active antiretroviral therapy (HAART) is not fully known …

HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral
variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus …

Despite our ability to suppress HIV-1 replication indefinitely in people on optimal combined
antiretroviral therapy (cART), HIV-1 persists as a stably integrated and replication-competent …

Background Antiretroviral therapy (ART) cannot cure HIV infection because of a persistent
reservoir of latently infected cells. Approaches that force HIV transcription from these cells …

Despite the success of antiretroviral therapy (ART) in decreasing mortality for HIV-1-infected
patients, ART has not cured the disease. A persistent viral reservoir in the T cells of HIV …

Autologous transplantation and engraftment of HIV-resistant cells in sufficient numbers
should recapitulate the functional cure of the Berlin Patient, with applicability to a greater …