Uridine metabolism is extensively reported to be involved in combating oxidative stress.
Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung …

Acute lung injury (ALI) causes high morbidity and mortality rates in critically ill patients, and
there are currently no effective therapeutic drugs. Ferroptosis is a newly discovered mode of …

Itaconate, a metabolite produced during inflammatory macrophage activation, has been
extensively described to be involved in immunoregulation, oxidative stress, and lipid …

Ferroptosis is a form of regulated nonapoptotic cell death associated with iron-dependent
lipid peroxidation. Previous studies have shown that ferroptosis is involved in the occurrence …

Background. Ferroptosis is a nonapoptotic form of programmed cell death, which may be
related to the occurrence and development of sepsis‐induced acute respiratory distress …

Context Ferulic acid (FA) has antioxidative and anti-inflammatory effects, and is a promising
drug to treat sepsis. Objective To study the therapeutic effect of FA in sepsis-induced acute …

Acute lung injury (ALI) carries a mortality rate of~ 50% and is a hot topic in the world of
critical illness research. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a critical …

Background The AU-rich element (ARE)-binding factor 1 (AUF1) acts as a switch for septic
shock, although its underlying mechanisms remain largely unknown. In this study, we …

Acute lung injury (ALI) is a life-threatening disease with high incidence and mortality rates.
Urolithin A (UA) is a pomegranate intestinal flora metabolite with anti-inflammatory …

Background Acute lung injury (ALI) is associated with high morbidity and mortality and is
partly driven promoted by ferroptosis. Proanthocyanidins (PAs) is a natural bioactive …