Stathmin 1: a novel therapeutic target for anticancer activity

S Rana, PB Maples, N Senzer… - Expert review of …, 2008 - Taylor & Francis
Stathmin 1 (STMN1), also known as p17, p18, p19, 19K, metablastin, oncoprotein 18, LAP
18 and Op18, is a 19 kDa cytosolic protein. It was the first discovered member of a family of …

Stathmin 1: a protein with many tasks. New biomarker and potential target in cancer

J Nemunaitis - Expert Opinion on Therapeutic Targets, 2012 - Taylor & Francis
Full article: Stathmin 1: a protein with many tasks. New biomarker and potential target in
cancer Skip to Main Content Taylor and Francis Online homepage Taylor and Francis Online …

Inhibition of stathmin1 accelerates the metastatic process

K Williams, R Ghosh, PV Giridhar, G Gu, T Case… - Cancer research, 2012 - AACR
Abstract The oncoprotein stathmin 1 (STMN1) is upregulated in most, if not all, cancers of
epithelial cell origin; therefore STMN1 is considered a target for cancer therapy. However, its …

Stathmin 1 is a potential novel oncogene in melanoma

J Chen, M Abi-Daoud, A Wang, X Yang, X Zhang… - Oncogene, 2013 - nature.com
In previous studies, we demonstrated that miR-193b expression is reduced in melanoma
relative to benign nevi, and also that miR-193b represses cyclin D1 and Mcl-1 expression …

[HTML][HTML] Overexpression of stathmin 1 is a poor prognostic biomarker in non-small cell lung cancer

W Nie, M Xu, L Gan, H Huang, Q Xiu, B Li - Laboratory investigation, 2015 - Elsevier
Abstract Stathmin 1 (STMN1), a major microtubule-depolymerizing protein, is involved in cell
cycle progression and cell motility. However, the clinical significance of STMN1 expression …

Stathmin1 overexpression associated with polyploidy, tumor‐cell invasion, early recurrence, and poor prognosis in human hepatoma

SY Hsieh, SF Huang, MC Yu, TS Yeh… - … in cooperation with …, 2010 - Wiley Online Library
Frequent intrahepatic metastasis causes early tumor recurrence and dismaying prognosis of
human hepatocellular carcinoma (HCC). We recently identified overexpression of stathmin1 …

[HTML][HTML] High STMN1 level is associated with chemo-resistance and poor prognosis in gastric cancer patients

T Bai, T Yokobori, B Altan, M Ide, E Mochiki… - British journal of …, 2017 - nature.com
Background: Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular
microtubule dynamics and is known to have oncogenic activity. Despite several reports, its …

Stathmin: a protein with many tasks. New biomarker and potential target in cancer

B Belletti, G Baldassarre - Expert opinion on therapeutic targets, 2011 - Taylor & Francis
Introduction: Stathmin is a microtubule-destabilizing phosphoprotein, firstly identified as the
downstream target of many signal transduction pathways. Several studies then indicated …

[HTML][HTML] Stathmin1 expression is associated with aggressive phenotypes and cancer stem cell marker expression in breast cancer patients

S Obayashi, J Horiguchi, T Higuchi… - International …, 2017 - spandidos-publications.com
Abstract Stathmin1 (STMN1) regulates progression in various cancers. The present study
aimed to determine the relationship between STMN1 expression and several cancer-related …

[HTML][HTML] Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer

W Kang, JHM Tong, AWH Chan, RWM Lung, SL Chau… - Plos one, 2012 - journals.plos.org
Stathmin1 (STMN1) is a candidate oncoprotein and prognosis marker in several kinds of
cancers. This study was aimed to analyze its expression and biological functions in gastric …