Challenges in sexual medicine

S Cellek, A Giraldi - Nature Reviews Urology, 2012 - nature.com
The sexual medicine field has been in mode of revolution until recently. Like all other fields
of biomedical research, the economic situation around the world has had a negative impact …

The safety of phosphodiesterase type 5 inhibitors for erectile dysfunction

E Ventimiglia, P Capogrosso, F Montorsi… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Phosphodiesterase type 5 inhibitors (PDE5Is) are the leading drugs for the
treatment of erectile dysfunction (ED), being recommended as a first line treatment by both …

PDE5 inhibitor treatment options for urologic and non-urologic indications: 2012 update

S Gur, PJ Kadowitz, E Can Serefoglu… - Current …, 2012 - ingentaconnect.com
Phosphodiesterase (PDE) enzymes are widely distributed throughout the body, having
numerous effects and functions. The use of on demand PDE5 inhibitors (-Is) for the treatment …

PDE-5 inhibition and sexual response: pharmacological mechanisms and clinical outcomes

RC Rosen, KE McKenna - Annual review of sex research, 2002 - Taylor & Francis
Abstract Phosphodiesterase type-5 (PDE-5) inhibitors are a new class of vasoactive drugs
that have been developed for treatment of erectile dysfunction (ED). The mechanism of …

Treatment of erectile dysfunction and lower urinary tract symptoms by phosphodiesterase inhibitors

S Ückert, CG Stief - Phosphodiesterases as Drug Targets, 2011 - Springer
To date, it is widely accepted that several disorders of the male and female urogenital tract,
such as erectile dysfunction, bladder overactivity, urinary stone disease, the benign prostatic …

Phosphodiesterase 5 inhibitors in male sexual dysfunction

A Kuthe - Current opinion in urology, 2003 - journals.lww.com
Phosphodiesterase 5 inhibitors in male sexual dysfunction : Current Opinion in Urology
Phosphodiesterase 5 inhibitors in male sexual dysfunction : Current Opinion in Urology Log in …

[PDF][PDF] Type 5 phosphodiesterase inhibitors: curing erectile dysfunction

WJG Hellstrom, M Kendirci - european urology, 2006 - Citeseer
Basic science research on erectile physiology has focused on the pathogenesis of erectile
dysfunction (ED) and has provided convincing evidence that ED is predominately a disease …

Phosphodiesterase type 5 inhibitors: the day after

K Hatzimouratidis, D Hatzichristou - European urology, 2007 - Elsevier
OBJECTIVE: Review the literature on phosphodiesterase type 5 inhibitors (PDE5-Is),
addressing critical issues in their current and future use, assessing unanswered questions …

Phosphodiesterase type 5 inhibitors for erectile dysfunction

CC Carson, TF Lue - BJU international, 2005 - Wiley Online Library
This is our first presentation of Great Drug Classes, and we start with a description of
phosphodiesterase type 5 inhibitors and their use in erectile dysfunction. This is an in‐depth …

New achievement and novel therapeutic applications of PDE5 inhibithors in older males.

GV Frajese, F Pozzi - Journal of Endocrinological Investigation, 2005 - europepmc.org
Erectile dysfunction (ED) increases in prevalence and severity because of aging processes
and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is …