FOXP transcription factors in vertebrate brain development, function, and disorders
M Co, AG Anderson, G Konopka - Wiley Interdisciplinary …, 2020 - Wiley Online Library
FOXP transcription factors are an evolutionarily ancient protein subfamily coordinating the
development of several organ systems in the vertebrate body. Association of their genes …
development of several organ systems in the vertebrate body. Association of their genes …
Understanding language from a genomic perspective
SA Graham, SE Fisher - Annual review of genetics, 2015 - annualreviews.org
Language is a defining characteristic of the human species, but its foundations remain
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …
Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria
SJ Turner, MS Hildebrand, S Block… - American journal of …, 2013 - Wiley Online Library
Relatively little is known about the neurobiological basis of speech disorders although
genetic determinants are increasingly recognized. The first gene for primary speech disorder …
genetic determinants are increasingly recognized. The first gene for primary speech disorder …
FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis
The expression patterns of the transcription factor FOXP2 in the developing mammalian
forebrain have been described, and some studies have tested the role of this protein in the …
forebrain have been described, and some studies have tested the role of this protein in the …
Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons
HY Kuo, SY Chen, RC Huang, H Takahashi, YH Lee… - Brain, 2023 - academic.oup.com
Human speech and language are among the most complex motor and cognitive abilities.
The discovery of a mutation in the transcription factor FOXP2 in KE family members with …
The discovery of a mutation in the transcription factor FOXP2 in KE family members with …
Assessing the impact of FOXP1 mutations on developmental verbal dyspraxia
Neurodevelopmental disorders that disturb speech and language are highly heritable.
Isolation of the underlying genetic risk factors has been hampered by complexity of the …
Isolation of the underlying genetic risk factors has been hampered by complexity of the …
Molecular genetics of speech and language disorders
DF Newbury, AP Monaco - Current opinion in pediatrics, 2002 - journals.lww.com
In 2001, scientists characterized the first gene to be implicated in the cause of a speech and
language disorder (FOXP2). Although FOXP2 was discovered using a unique family in …
language disorder (FOXP2). Although FOXP2 was discovered using a unique family in …
FoxP2 regulates neurogenesis during embryonic cortical development
D Tsui, JP Vessey, H Tomita, DR Kaplan… - Journal of …, 2013 - Soc Neuroscience
The transcription factor FoxP2 has been associated with the development of human speech
but the underlying cellular function of FoxP2 is still unclear. Here we provide evidence that …
but the underlying cellular function of FoxP2 is still unclear. Here we provide evidence that …
Genetic components of vocal learning
Vocal learning is a rare trait. Humans depend on vocal learning to acquire spoken
language, but most species that communicate acoustically have an innate repertoire of …
language, but most species that communicate acoustically have an innate repertoire of …
FoxP2 regulation during undirected singing in adult songbirds
I Teramitsu, SA White - Journal of Neuroscience, 2006 - Soc Neuroscience
Learned vocal communication, including human speech, is a socially influenced behavior
limited to certain animals. This ability requires auditory feedback during vocalization, which …
limited to certain animals. This ability requires auditory feedback during vocalization, which …