Background Rare mutations affecting the FOXP2 transcription factor cause a monogenic
speech and language disorder. We hypothesized that neural pathways downstream of …

Abstract Genes including FOXP2, FOXP1, and CNTNAP2, have been implicated in human
speech and language phenotypes, pointing to a role in the development of normal language …

This article gives an overview on the various brain structures, other than neocortex,
contributing to speech and language. The regions of the avian brain which are considered …

Abstract Mental retardation affects 2‐3% of the population and shows a high heritability.
Neurodevelopmental disorders that include pronounced impairment in language and …

We genotyped a healthy population for three haplotype-tagging FOXP2 SNPs, and tested for
associations of these SNPs with strength of handedness and questionnaire-based metrics of …

Foxp2 and Foxp1 are recently identified members of the Fox family of winged‐helix/forkhead
transcription factor genes. A recent study has found that mutations in human FOXP2 produce …

The evolution of novel morphological features, such as feathers, involves the modification of
developmental processes regulated by gene networks. The fact that genetic novelty …

Genetic disruptions of the forkhead box transcription factor FOXP2 in humans cause an
autosomal-dominant speech and language disorder. While FOXP2 expression pattern are …

The integration of language pathologies, genetics, brain imaging, molecular embryology,
and sequential gene expression, by means of DNA/RNA/proteomics, is a remarkable open …

The closely related paralogues FOXP2 and FOXP1 encode transcription factors with shared
functions in the development of many tissues, including the brain. However, while mutations …