Human speech involves species-specific anatomy deriving from the descent of the tongue
into the pharynx. The human tongue's shape and position yields the 1: 1 oral-to-pharyngeal …

Genes responsible for human-specific phenotypes may have been under altered selective
pressures in human evolution and thus exhibit changes in substitution rate and pattern at the …

The identification of the first gene involved in a speech-language disorder was made
possible through the study of a British multi-generational family (the “KE family”) in whom …

Mutations in the human FOXP2 gene cause impaired speech development and linguistic
deficits, which have been best characterised in a large pedigree called the KE family. The …

Although a mutation (R553H) in the forkhead box (FOX) P2 gene is associated with
speech/language disorder, little is known about the function of FOXP2 or its relevance to this …

Forkhead domain transcription factors are a large gene family with multiple roles in
development. FOXP2, a recently identified member of this family, has been shown to be …

The FOXP2 gene is required for normal development of speech and language. By isolating
and sequencing FOXP2 genomic DNA fragments from a 49,000-year-old Iberian Neandertal …

Researchers are beginning to uncover the neurogenetic pathways that underlie our
unparalleled capacity for spoken language. Initial clues come from identification of genetic …

Human Evolution: Neandertal Gene Speaks out Page 1 finding that myosin VI association with
endocytic vesicles promotes dimerization, a switch likely to be essential for processive …

The view that language evolved from a primarily gestural mode of communication has its
roots on the 18th-century philosophers speculations (Vico, 1953/1744; de Condillac …