Impact: This study explores the use of measuring plasma biomarkers at exacerbation of
chronic obstructive pulmonary disease (COPD), providing insight into the underlying …

Importance Exacerbations of respiratory symptoms in chronic obstructive pulmonary disease
(COPD) have profound and long-lasting adverse effects on patients. Objective To test the …

The aims of this systematic review were to determine which blood-based molecules have
been evaluated as possible biomarkers to diagnose chronic obstructive pulmonary disease …

Background Exacerbations of COPD (ECOPD) remain a major cause of mortality and
morbidity. Despite advances in the understanding of their pathophysiology, their assessment …

Background Mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR) and platelet-
to-lymphocyte ratio (PLR) have all been investigated as novel inflammatory markers of …

Rationale: Patients with chronic obstructive pulmonary disease (COPD) have an ongoing
systemic inflammation, which can be assessed by measuring serum C-reactive protein …

Rationale: Exacerbations of chronic obstructive pulmonary disease (COPD) are
heterogeneous with respect to inflammation and etiology. Objectives: Investigate biomarker …

Objectives We aimed to investigate the importance of neutrophil–lymphocyte ratio (NLR) in
patients with chronic obstructive pulmonary disease (COPD) for identifying the severity of …

Background: C-reactive protein (CRP) is often used as a clinical marker of acute systemic
inflammation. Since low grade inflammation is evident in chronic diseases such as chronic …

Exacerbations of COPD (ECOPD) represent a major burden for patients and health care
systems. Innovative sampling techniques have led to the identification of several pulmonary …