Considering malaria is a highly devastating disease of mankind, total eradication of malaria
seems to be an uphill task, the only relief from this disease is achieved by usage of …

Introduction Artemisinin-based combination therapies (ACTs) are recommended first-line
antimalarials for uncomplicated Plasmodium falciparum malaria. Pharmacokinetic …

Introduction: Plasmodium falciparum malaria is one of the world's most lethal infectious
diseases, commanding millions of drug administrations per year. The pharmacogenetics of …

Malaria is a vector-borne infectious disease caused by protozoan parasites of the genus
Plasmodium. If not treated appropriately, human P. falciparum malaria can quickly become …

Malaria ranks with tuberculosis and AIDS in terms of its ability to destroy human health. In
India there are at least two million cases seen annually. Although mortality may not be as …

Malaria, a disease transmitted by the female Anopheles mosquito, has had devastating
effects on human populations for more than 4000 years. Treatment of the disease with single …

Over the last 5 years, there has been an increased investment in malaria medicines, with the
emergence of a range of new fixed dose artemisinin combination therapies (FACTs). Of the …

Highlights•New targets and resistance determinants have been identified for ACT partner
drugs.•Resistance to many of the ACT partner drugs involves multifactorial mechanisms.• …

Parasite Paradise - Antimalarials: Between Health and a Hard Place Page 1 Malaria, a disease
of poverty, currently kills between one and two million humans every year and causes 500 …

Artemisinin is an antimalarial compound derived from the plant Artemisia annua L., also
known as sweet wormwood. According to the World Health Organization, artemisinin‐based …