Programmed cell death is a basic cellular process that is critical to maintain tissue
homeostasis. Besides apoptosis, necroptosis has more recently been discovered as another …

Evasion of programmed cell death represents one of the hallmarks of cancers that
contributes to tumor initiation, progression and treatment resistance. This calls for novel …

Necroptosis | New England Journal of Medicine Skip to main content The New England Journal
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Necroptosis is an emerging form of programmed cell death occurring via active and well-
regulated necrosis, distinct from apoptosis morphologically, and biochemically. Necroptosis …

Over the past few decades, mechanisms of programmed cell death have attracted the
scientific community because they are involved in diverse human diseases. Initially …

Necroptosis refers to a regulated form of cell death induced by a variety of stimuli. Although it
has been implicated in the pathogenesis of many diseases, there is evidence to support that …

Necroptosis is a programmed, caspase-independent cell death that is morphologically
similar to necrosis. Unlike apoptosis, necroptosis evokes inflammatory responses by …

Resistance to caspase‐dependent apoptosis is often responsible for treatment failures in
cancer. Finding novel therapeutic strategies that can activate alternative cell death programs …

Regulated cell death is one major factor to ensure homoeostasis in multicellular organisms.
For decades, apoptosis was considered as the sole form of regulated cell death, whereas …

Necroptosis, a form of programmed necrotic cell death, is a gatekeeper of host defense
against certain pathogen invasions. The deregulation of necroptosis is also a key factor of …