Inactivation of AMPKα1 induces asthenozoospermia and alters spermatozoa morphology
P Tartarin, E Guibert, A Touré, C Ouiste… - …, 2012 - academic.oup.com
AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis, is
present in metabolic tissues (muscle and liver) and has been identified as a modulator of the …
present in metabolic tissues (muscle and liver) and has been identified as a modulator of the …
Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality
MJ Bertoldo, E Guibert, M Faure, F Guillou… - Molecular and Cellular …, 2016 - Elsevier
The AMP-activated protein kinase (AMPK) is an important regulator of cellular energy
homeostasis which plays a role in fertility. Complete disruption of the AMPK catalytic subunit …
homeostasis which plays a role in fertility. Complete disruption of the AMPK catalytic subunit …
AMPK function in mammalian spermatozoa
D Martin-Hidalgo, A Hurtado de Llera… - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase AMPK regulates cellular energy by controlling metabolism
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …
Roles of AMP-activated protein kinase (AMPK) in mammalian reproduction
W Yang, L Wang, F Wang, S Yuan - Frontiers in Cell and …, 2020 - frontiersin.org
Reproduction is an energy demanding function and only take place in case of sufficient
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …
AMP-activated kinase in human spermatozoa: identification, intracellular localization, and key function in the regulation of sperm motility
V Calle-Guisado, AH de Llera… - Asian Journal of …, 2017 - journals.lww.com
Abstract AMP-activated kinase (AMPK), a protein that regulates energy balance and
metabolism, has recently been identified in boar spermatozoa where regulates key …
metabolism, has recently been identified in boar spermatozoa where regulates key …
AMP-activated kinase AMPK is expressed in boar spermatozoa and regulates motility
A Hurtado de Llera, D Martin-Hidalgo, MC Gil… - PloS one, 2012 - journals.plos.org
The main functions of spermatozoa required for fertilization are dependent on the energy
status and metabolism. AMP-activated kinase, AMPK, acts a sensor and regulator of cell …
status and metabolism. AMP-activated kinase, AMPK, acts a sensor and regulator of cell …
AMPK: a master energy regulator for gonadal function
From C. elegans to mammals (including humans), nutrition and energy metabolism
significantly influence reproduction. At the cellular level, some detectors of energy status …
significantly influence reproduction. At the cellular level, some detectors of energy status …
Impact of 5'-amp-activated protein kinase on male gonad and spermatozoa functions
TMD Nguyen - Frontiers in Cell and Developmental Biology, 2017 - frontiersin.org
As we already know, the male reproductive system requires less energetic investment than
the female one. Nevertheless, energy balance is an important feature for spermatozoa …
the female one. Nevertheless, energy balance is an important feature for spermatozoa …
Role of AMPK in mammals reproduction: Specific controls and whole-body energy sensing
TMD Nguyen - Comptes Rendus Biologies, 2019 - Elsevier
AMP-activated protein kinase (AMPK) is a key enzyme involved in linking the energy
sensing to metabolic pathways. As such, it plays a central role at the whole-body level to …
sensing to metabolic pathways. As such, it plays a central role at the whole-body level to …
The calcium/CaMKKalpha/beta and the cAMP/PKA pathways are essential upstream regulators of AMPK activity in boar spermatozoa
A Hurtado de Llera, D Martin-Hidalgo… - Biology of …, 2014 - academic.oup.com
Spermatozoa successfully fertilize oocytes depending on cell energy-sensitive processes.
We recently showed that the cell energy sensor, the AMP-activated protein kinase (AMPK) …
We recently showed that the cell energy sensor, the AMP-activated protein kinase (AMPK) …