Advances in molecular biological techniques combined with pharmacologic and signal
transduction assays have greatly accelerated our understanding of the heterogeneity of …

We developed and characterized 14 polyclonal antibodies against peptides whose
sequences were predicted from the type 3 serotonin receptor subunit A (5-HT3R-A) cDNA …

Abstract Serotonin (5‐HT) mediates its effects on neurons in the central nervous system
through a number of different receptor types. To gain better insight as to the localization of 5 …

Serotonin [5-hydroxytryptamine (5-HT)] is a neuromodulator that mediates a wide range of
physiological functions by activating multiple receptors. Using a strategy based on amino …

The serotonin 5-HT3 receptor subtype has been implicated in many brain functions.
Antagonists of this receptor have anxiolytic and antiemetic effects in humans and in animal …

The gene and cDNAs that encode a novel subunit of rodent serotonin 5‐HT3 receptors were
isolated from mouse and rat tissues. Each of the new rodent subunits shares 40% amino …

Because of their similarities, serotonin 5-HT 2, 5-HT 1C, and the recently described 5-HT 2F
receptors have been classified as members of the 5-HT 2 receptor family, and they have …

We and others have recently cloned the genes encoding the human 5-HT 1D (5-HT 1Dα)
and 5-HT 1B (5-HT 1Dβ) serotonin receptors. Because of the history of profound species …

We describe the cloning and characterization of a human 5‐HT6 serotonin receptor. The
open reading frame is interrupted by two introns in positions corresponding to the third …

Degenerate primers, suitable for polymerase chain reaction studies and based on the
conserved structure of G protein-coupled receptors, were used to isolate cDNA clones …