Many of the proteins and their encoding genes involved in spermatogenesis are unknown,
making the specific diagnosis and treatment of infertility in males difficult and highlighting the …

Infertility is defined as the inability of a couple to conceive despite trying for a year, and it
affects approximately 15% of the reproductive‐age population. It is considered a genetically …

Spermatogenesis describes a complex multistep differentiation process to produce millions
of mature spermatozoa daily. Spermatogenesis is fueled by spermatogonial stem cells. It …

In this chapter I shall review evidence for direct genetic control of spermatogenesis in mice
from two perspectives. First, I shall consider genetic conditions affecting the process of …

An increasing number of genetically engineered animals are produced worldwide for use in
both basic and applied research. Here, I provide an update of some of the latest mouse …

After colonization of the gonad, mouse female germ cells enter into the prophase of the first
meiotic division as a mid-gestational hallmark of gender. Perinatally, oocytes interact with …

Mammalian fertilization comprises sperm migration through the female reproductive tract,
biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct …

32.4 CONCLUSION Increasingly, additional genes are being identified to cause the most
severe forms of infertility in females. These findings have improved our understanding of …

BACKGROUND Functional male gametes are produced through complex processes that
take place within the testis, epididymis and female reproductive tract. A breakdown at any of …