Cysteine (CYS) is a non-essential amino acid which elicits excitotoxic properties via the N-
methyl-D-aspartate (NMDA) subtype of the glutamate receptor. CYS levels are known to be …

Cysteine and its metabolites cysteine sulphinic acid (CSA) and taurine (TA) were shown to
be toxic to human and rat neuronal cell lines. However, the mechanisms of action of CSA …

We review here the possible mechanisms of neuronal degeneration caused by L-cysteine,
an odd excitotoxin. L-Cysteine lacks the omega carboxyl group required for excitotoxic …

l-Cysteine produces excitotoxic brain damage but its chemical structure differs from that of
other excitotoxins. Although it is an NMDAmimetic, its mode of action is complex and may …

Excitotoxic amino acids contain two acidic groups, but cysteine represents an exception to
this rule. The hypothesis that cysteine toxicity is mediated by the oxidized and diacidic …

The mechanisms underlying cell damage in stroke or during experimental brain ischemia
are not fully understood. l-Cyteine, an excitotoxic amino acid that could contribute to tissue …

Recent work from humans and chick embryos has suggested that homocysteine may play a
role in producing neural tube defects (NTDs). In an effort to determine if homocysteine is …

Homocysteine (HC) is a neurotoxic amino acid that accumulates in several neurological
disorders including Alzheimer's disease (AD). We examined the consequences of treatment …

After systemic administration to immature rodents, L-cysteine destroys neurons in the
cerebral cortex, hippocampus, thalamus, and striatum, but the underlying mechanism has …

The rat hippocampal slice preparation and its electrophysiology were used to assess the
toxicity of two sulfur-containing amino acids, l-cysteate (CA) and l-cysteine (CYS). Both …