Multiple sclerosis (MS) is a chronic neurological disease of the central nervous system
driven by peripheral immune cell infiltration and glial activation. The pathological hallmark of …

In multiple sclerosis (MS), pathogenic T cell responses are known to be important drivers of
autoimmune inflammation. However, increasing evidence suggests an additional role for B …

Multiple sclerosis (MS) is characterized by central nervous system (CNS) inflammation,
demyelination, and axonal degeneration. CXCL10 (IP-10), a chemokine for CXCR3+ T cells …

Background The mechanisms driving multiple sclerosis (MS), the most common cause of
non-traumatic disability in young adults, remain unknown despite extensive research …

Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous
system (CNS). Bone marrow hematopoietic stem and progenitor cells (HSPCs) rapidly …

Multiple sclerosis (MS) is characterized by pathological inflammation that results from the
recruitment of lymphoid and myeloid immune cells from the blood into the brain. Due to …

Brain infiltration of peripheral immune cells and their interactions with brain-resident cells
may contribute to Alzheimer's disease (AD) pathology. To examine these interactions, in the …

Multiple Sclerosis (MS) is an inflammatory disease of the Central Nervous System (CNS)
that causes the demyelination of nerve cells and destroys oligodendrocytes, neurons and …

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the CNS. Although
CD4+ T cells are implicated in MS pathogenesis and have been the main focus of MS …

Molecular interventions that limit pathogenic CNS inflammation are used to treat
autoimmune conditions such as multiple sclerosis (MS). Remarkably, IL-1β–knockout mice …