The adoptive transfer of myelin-reactive T cells into wild-type hosts results in spinal cord
inflammation and ascending paralysis, referred to as conventional experimental …

Dendritic cells (DCs)—although absent from the healthy CNS parenchyma—rapidly
accumulate within brain and spinal cord tissue during neuroinflammation associated with …

To study the role of myeloid cells in the central nervous system (CNS) in the pathogenesis of
multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system that
is believed to have an autoimmune origin. CD4+ T cells have been well studied for their …

In both multiple sclerosis and its model experimental autoimmune encephalomyelitis (EAE),
the extent of resident microglia activation and infiltration of monocyte-derived cells to the …

Two distinct clinical phenotypes of experimental autoimmune encephalomyelitis are
observed in BALB interferon-γ knockout mice immunized with encephalitogenic peptides of …

Background Multiple sclerosis (MS), an autoimmune disease of the central nervous system
(CNS), can be suppressed in its early stages but eventually becomes clinically progressive …

Multiple Sclerosis (MS) is a neurodegenerative autoimmune disorder of the central nervous
system (CNS) characterized by the recruitment of self-reactive T lymphocytes, mainly …

The role of CD8+ T cells in multiple sclerosis (MS) and experimental autoimmune
encephalomyelitis (EAE) is still unclear. We describe here significantly reduced disease …

During multiple sclerosis (MS), an inflammatory and neurodegenerative disease of the
central nervous system (CNS), symptoms, and outcomes are determined by the location of …