Ventral tegmental area dopamine cell activation during male rat sexual behavior regulates neuroplasticity and d-amphetamine cross-sensitization following sex …
Experience with sexual behavior causes cross-sensitization of amphetamine reward, an
effect dependent on a period of sexual reward abstinence. We previously showed that …
effect dependent on a period of sexual reward abstinence. We previously showed that …
Endogenous opioid-induced neuroplasticity of dopaminergic neurons in the ventral tegmental area influences natural and opiate reward
KK Pitchers, CM Coppens, LN Beloate… - Journal of …, 2014 - Soc Neuroscience
Natural reward and drugs of abuse converge on the mesolimbic pathway and activate
common mechanism of neural plasticity in the nucleus accumbens. Chronic exposure to …
common mechanism of neural plasticity in the nucleus accumbens. Chronic exposure to …
Neuroplasticity in the mesolimbic system induced by natural reward and subsequent reward abstinence
KK Pitchers, ME Balfour, MN Lehman, NM Richtand… - Biological …, 2010 - Elsevier
BACKGROUND: Natural reward and drugs of abuse converge on the mesolimbic system,
where drugs of abuse induce neuronal alterations. Here, we tested plasticity in this system …
where drugs of abuse induce neuronal alterations. Here, we tested plasticity in this system …
Natural and drug rewards act on common neural plasticity mechanisms with ΔFosB as a key mediator
KK Pitchers, V Vialou, EJ Nestler… - Journal of …, 2013 - Soc Neuroscience
Drugs of abuse induce neuroplasticity in the natural reward pathway, specifically the
nucleus accumbens (NAc), thereby causing development and expression of addictive …
nucleus accumbens (NAc), thereby causing development and expression of addictive …
Nucleus accumbens NMDA receptor activation regulates amphetamine cross-sensitization and deltaFosB expression following sexual experience in male rats
Sexual experience in male rats followed by a period of abstinence causes sensitization to d-
Amphetamine (Amph) reward, evidenced by an increased conditioned place preference …
Amphetamine (Amph) reward, evidenced by an increased conditioned place preference …
[HTML][HTML] Natural reward experience alters AMPA and NMDA receptor distribution and function in the nucleus accumbens
KK Pitchers, S Schmid, AR Di Sebastiano, X Wang… - PloS one, 2012 - journals.plos.org
Natural reward and drugs of abuse converge upon the mesolimbic system which mediates
motivation and reward behaviors. Drugs induce neural adaptations in this system, including …
motivation and reward behaviors. Drugs induce neural adaptations in this system, including …
Sexual behavior induction of c-Fos in the nucleus accumbens and amphetamine-stimulated locomotor activity are sensitized by previous sexual experience in female …
KC Bradley, RL Meisel - Journal of Neuroscience, 2001 - Soc Neuroscience
Dopamine transmission in the nucleus accumbens can be activated by drugs, stress, or
motivated behaviors, and repeated exposure to these stimuli can sensitize this dopamine …
motivated behaviors, and repeated exposure to these stimuli can sensitize this dopamine …
[HTML][HTML] Sexual behavior and sex-associated environmental cues activate the mesolimbic system in male rats
The mesolimbic system plays an important role in the regulation of both pathological
behaviors such as drug addiction and normal motivated behaviors such as sexual behavior …
behaviors such as drug addiction and normal motivated behaviors such as sexual behavior …
Influences of social reward experience on behavioral responses to drugs of abuse: review of shared and divergent neural plasticity mechanisms for sexual reward and …
LN Beloate, LM Coolen - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Different factors influence the development of drug addiction in humans, including social
reward experiences. In animals, experience with social rewards, such as sexual behavior …
reward experiences. In animals, experience with social rewards, such as sexual behavior …
Cell-type specific increases in female hamster nucleus accumbens spine density following female sexual experience
NA Staffend, VL Hedges, BR Chemel, VJ Watts… - Brain Structure and …, 2014 - Springer
Female sexual behavior is an established model of a naturally motivated behavior which is
regulated by activity within the mesolimbic dopamine system. Repeated activation of the …
regulated by activity within the mesolimbic dopamine system. Repeated activation of the …