Repeatability of fractional flow reserve despite variations in systemic and coronary hemodynamics

NP Johnson, DT Johnson, RL Kirkeeide, C Berry… - JACC: Cardiovascular …, 2015 - jacc.org
Objectives: This study classified and quantified the variation in fractional flow reserve (FFR)
due to fluctuations in systemic and coronary hemodynamics during intravenous adenosine …

Hemodynamic response to intravenous adenosine and its effect on fractional flow reserve assessment: results of the Adenosine for the Functional Evaluation of …

JM Tarkin, S Nijjer, S Sen, R Petraco… - Circulation …, 2013 - Am Heart Assoc
Background—We studied the hemodynamic response to intravenous adenosine on
calculation of fractional flow reserve (FFR). Intravenous adenosine is widely used to achieve …

Comparison of intracoronary versus intravenous administration of adenosine for measurement of coronary fractional flow reserve

C Schlundt, C Bietau, L Klinghammer… - Circulation …, 2015 - Am Heart Assoc
Background—Measurement of fractional flow reserve (FFR) constitutes the current gold
standard to evaluate the hemodynamic significance of coronary stenoses. Limited data …

VERIFY (VERification of instantaneous wave-free ratio and fractional flow reserve for the assessment of coronary artery stenosis severity in EverydaY practice) a …

C Berry, M Van'T Veer, N Witt, P Kala, O Bocek… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to compare fractional flow reserve (FFR) with the
instantaneous wave-free ratio (iFR) in patients with coronary artery disease and also to …

Variations of coronary hemodynamic responses to intravenous adenosine infusion: implications for fractional flow reserve measurements

AH Seto, DM Tehrani, MI Bharmal… - Catheterization and …, 2014 - Wiley Online Library
Background Continuous intravenous adenosine infusion reportedly produces stable and
maximal hyperemia to allow for fractional flow reserve (FFR) measurement; however …

Effects of increasing doses of intracoronary adenosine on the assessment of fractional flow reserve

G De Luca, L Venegoni, S Iorio, L Giuliani… - JACC: Cardiovascular …, 2011 - jacc.org
Objectives: The purpose of this study was to investigate the effects of increasing dose of
intracoronary adenosine on fractional flow reserve (FFR) measurement. Backgrounds: FFR …

Continuum of vasodilator stress from rest to contrast medium to adenosine hyperemia for fractional flow reserve assessment

NP Johnson, A Jeremias, FM Zimmermann… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: This study compared the diagnostic performance with adenosine-derived
fractional flow reserve (FFR)≤ 0.8 of contrast-based FFR (cFFR), resting distal pressure …

Adequacy of intracoronary versus intravenous adenosine-induced maximal coronary hyperemia for fractional flow reserve measurements

A Jeremias, RJ Whitbourn, SD Filardo… - American heart …, 2000 - Elsevier
Background Fractional flow reserve (FFR) is a measure of coronary stenosis severity that is
based on pressure measurements obtained at maximal hyperemia. The most widely used …

Accuracy of fractional flow reserve measurements in clinical practice: observations from a core laboratory analysis

M Matsumura, NP Johnson, WF Fearon… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to compare site-reported measurements of fractional
flow reserve (FFR) with FFR analysis by an independent core laboratory (CL). Background …

Association of improvement in fractional flow reserve with outcomes, including symptomatic relief, after percutaneous coronary intervention

S Fournier, G Ciccarelli, GG Toth, A Milkas… - JAMA …, 2019 - jamanetwork.com
Importance Whether the improvement in myocardial perfusion provided by percutaneous
coronary intervention (PCI) is associated with symptomatic relief or improved outcomes has …