Are high doses of intracoronary adenosine an alternative to standard intravenous adenosine for the assessment of fractional flow reserve?

G Casella, M Leibig, TM Schiele, R Schrepf… - American heart …, 2004 - Elsevier
BACKGROUND: Achievement of maximal hyperemia of the coronary microcirculation is a
prerequisite for the measurement of fractional flow reserve (FFR). Intravenous adenosine is …

Influence of hemodynamic conditions on fractional flow reserve: parametric analysis of underlying model

M Siebes, SAJ Chamuleau… - American Journal …, 2002 - journals.physiology.org
Pressure-based fractional flow reserve (FFR) is used clinically to evaluate the functional
severity of a coronary stenosis, by predicting relative maximal coronary flow (Qs/Qn). It is …

Fractional flow reserve in clinical practice: from wire-based invasive measurement to image-based computation

S Tu, J Westra, J Adjedj, D Ding, F Liang… - European Heart …, 2020 - academic.oup.com
Fractional flow reserve (FFR) and instantaneous wave-free ratio are the present standard
diagnostic methods for invasive assessment of the functional significance of epicardial …

A test in context: fractional flow reserve: accuracy, prognostic implications, and limitations

A Jeremias, AJ Kirtane, GW Stone - Journal of the American College of …, 2017 - jacc.org
Fractional flow reserve (FFR) is an invasive procedure used during coronary angiography to
determine the functional significance of coronary stenoses. Its use is particularly helpful in …

Prognostic value of fractional flow reserve: linking physiologic severity to clinical outcomes

NP Johnson, GG Tóth, D Lai, H Zhu, G Açar… - Journal of the American …, 2014 - jacc.org
Background: Fractional flow reserve (FFR) has become an established tool for guiding
treatment, but its graded relationship to clinical outcomes as modulated by medical therapy …

Physiological pattern of disease assessed by pressure-wire pullback has an influence on fractional flow reserve/instantaneous wave-free ratio discordance: Insights …

T Warisawa, CM Cook, JP Howard… - Circulation …, 2019 - Am Heart Assoc
Background: Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) disagree
on the hemodynamic significance of a coronary lesion in≈ 20% of cases. It is unknown …

Prognostic implication of thermodilution coronary flow reserve in patients undergoing fractional flow reserve measurement

JM Lee, KH Choi, D Hwang, J Park, JH Jung… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: This study investigated the prognostic implication of coronary flow reserve (CFR)
in patients who underwent fractional flow reserve (FFR) measurement. Background: Limited …

Rationale and design of the precise percutaneous coronary intervention plan (P3) study: prospective evaluation of a virtual computed tomography‐based …

S Nagumo, C Collet, BL Norgaard, H Otake… - Clinical …, 2021 - Wiley Online Library
Introduction Fractional flow reserve (FFR) measured after percutaneous coronary
intervention (PCI) has been identified as a surrogate marker for vessel related adverse …

Physiological basis and long-term clinical outcome of discordance between fractional flow reserve and coronary flow velocity reserve in coronary stenoses of …

TP van de Hoef, MA van Lavieren… - Circulation …, 2014 - Am Heart Assoc
Background—Discordance between fractional flow reserve (FFR) and coronary flow velocity
reserve (CFVR) may reflect important coronary pathophysiology but usually remains …

Feasibility and safety of intracoronary nicorandil infusion as a novel hyperemic agent for fractional flow reserve measurements

D Kato, H Takashima, K Waseda, A Kurita, Y Kuroda… - Heart and vessels, 2015 - Springer
Fractional flow reserve (FFR) is a useful modality to assess the functional significance of
coronary stenoses. Although adenosine triphosphate (ATP) is generally used as the …