Terpenoid metabolic engineering in photosynthetic microorganisms

K Vavitsas, M Fabris, CE Vickers - Genes, 2018 - mdpi.com
Terpenoids are a group of natural products that have a variety of essential and non-essential
roles in metabolism, in biotic and abiotic interactions, as well as commercial applications …

Engineering microbes for isoprene production

L Ye, X Lv, H Yu - Metabolic engineering, 2016 - Elsevier
Isoprene is facing a growing global market due to its wide industrial applications. Current
industrial production of isoprene is almost entirely petroleum-based, which is influenced by …

Methylerythritol phosphate pathway of isoprenoid biosynthesis

L Zhao, W Chang, Y Xiao, H Liu… - Annual review of …, 2013 - annualreviews.org
Isoprenoids are a class of natural products with more than 55,000 members. All isoprenoids
are constructed from two precursors, isopentenyl diphosphate and its isomer dimethylallyl …

Toward industrial production of isoprenoids in Escherichia coli: Lessons learned from CRISPR‐Cas9 based optimization of a chromosomally integrated mevalonate …

J Alonso‐Gutierrez, D Koma, Q Hu… - Biotechnology and …, 2018 - Wiley Online Library
Escherichia coli has been the organism of choice for the production of different chemicals by
engineering native and heterologous pathways. In the present study, we simultaneously …

Isoprenoid-based biofuels: homologous expression and heterologous expression in prokaryotes

SC Phulara, P Chaturvedi, P Gupta - Applied and environmental …, 2016 - Am Soc Microbiol
Enthusiasm for mining advanced biofuels from microbial hosts has increased remarkably in
recent years. Isoprenoids are one of the highly diverse groups of secondary metabolites and …

Building terpene production platforms in yeast

X Zhuang, J Chappell - Biotechnology and bioengineering, 2015 - Wiley Online Library
Plants and microbes commonly make terpenes and terpenoids in small amounts and as
complex mixtures, and their chemical synthesis is often costly and inefficient. Hence, there …

[PDF][PDF] Cell-free biosynthesis of limonene using enzyme-enriched Escherichia coli lysates

QM Dudley, CJ Nash, MC Jewett - Synthetic Biology, 2019 - academic.oup.com
Isoprenoids are an attractive class of metabolites for enzymatic synthesis from renewable
substrates. However, metabolic engineering of microorganisms for monoterpenoid …

Eukaryotic microalgae as hosts for light-driven heterologous isoprenoid production

KJ Lauersen - Planta, 2019 - Springer
Main conclusions Eukaryotic microalgae hold incredible metabolic potential for the
sustainable production of heterologous isoprenoid products. Recent advances in algal …

[HTML][HTML] Metabolic engineering for the high-yield production of isoprenoid-based C5 alcohols in E. coli

KW George, MG Thompson, A Kang, E Baidoo… - Scientific reports, 2015 - nature.com
Branched five carbon (C 5) alcohols are attractive targets for microbial production due to
their desirable fuel properties and importance as platform chemicals. In this study, we …

Engineering plant sesquiterpene synthesis into yeasts: a review

J Mai, W Li, R Ledesma-Amaro… - Journal of Agricultural and …, 2021 - ACS Publications
Sesquiterpenes are natural compounds composed of three isoprene units. They represent
the largest class of terpene compounds found in plants, and many have remarkable …