The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

The central nervous system (CNS) is a sanctuary site and is protected by various barriers.
These regulate brain homeostasis and the transport of endogenous and exogenous …

The brain is a complex, regulated organ with a highly controlled access mechanism: The
Blood-Brain Barrier (BBB). The selectivity of this barrier is a double-edged sword, being both …

The blood–brain barrier (BBB) provides a stable and safe environment for physiological
function of the central nervous system (CNS) as a protective barrier. However, the existence …

A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …

With estimated worldwide cost over $1 trillion just for dementia, diseases of the central
nervous system pose a major problem to health and healthcare systems, with significant …

Alzheimer's disease (AD) and treatment of the brain in aging require the development of
new biologic drugs, such as recombinant proteins or gene therapies. Biologics are large …

The blood brain barrier (BBB) maintains the homeostasis of the central nervous system
(CNS) and protects the brain from toxic substances present in the circulating blood …

Peptide and protein (P/P) drugs have been identified as showing great promises for the
treatment of various neurodegenerative diseases. A major challenge in this regard …

The blood brain barrier (BBB) offers protection to the central nervous system (CNS) by
maintaining homeostasis. Besides restricting the entry of harmful xenobiotics and …