Hypermetabolism in ALS is associated with greater functional decline and shorter survival

FJ Steyn, ZA Ioannides, RPA Van Eijk… - Journal of Neurology …, 2018 - jnnp.bmj.com
Objective To determine the prevalence of hypermetabolism, relative to body composition, in
amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and …

Alteration of nutritional status at diagnosis is a prognostic factor for survival of amyotrophic lateral sclerosis patients

B Marin, JC Desport, P Kajeu, P Jésus… - Journal of Neurology …, 2011 - jnnp.bmj.com
Objectives The aims were to analyse changes in nutritional parameters from diagnosis of
amyotrophic lateral sclerosis (ALS) to death and to assess their relationships with survival at …

Hypermetabolism is a deleterious prognostic factor in patients with amyotrophic lateral sclerosis

P Jésus, P Fayemendy, M Nicol… - European Journal of …, 2018 - Wiley Online Library
Background and purpose The aim of this study was to investigate patients with amyotrophic
lateral sclerosis in order to determine their nutritional, neurological and respiratory …

Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs?

N Vaisman, M Lusaus, B Nefussy, E Niv… - Journal of the …, 2009 - Elsevier
BACKGROUND AND AIMS: Nutritional status is a prognostic factor for survival in
amyotrophic lateral sclerosis (ALS) patients. We investigated the contribution of some of the …

Hypermetabolism in ALS patients: an early and persistent phenomenon

C Bouteloup, JC Desport, P Clavelou, N Guy… - Journal of …, 2009 - Springer
The malnutrition common among patients with ALS can be attributed in some cases to
increased resting energy expenditure (REE). However, the origins and evolution of this …

Prognostic significance of body weight variation after diagnosis in ALS: a single-centre prospective cohort study

T Shimizu, Y Nakayama, C Matsuda, M Haraguchi… - Journal of …, 2019 - Springer
Background Body weight reduction after disease onset is an independent predictor of
survival in amyotrophic lateral sclerosis (ALS), but significance of weight variation after …

[HTML][HTML] Factors correlated with hypermetabolism in patients with amyotrophic lateral sclerosis

JC Desport, PM Preux, L Magy, Y Boirie… - The American journal of …, 2001 - Elsevier
Background: Amyotrophic lateral sclerosis (ALS) is a severe disease characterized by
neurogenic amyotrophy and degeneration of upper and lower motor neurons. Although ALS …

Energy metabolism in amyotrophic lateral sclerosis

L Dupuis, PF Pradat, AC Ludolph… - The Lancet Neurology, 2011 - thelancet.com
Amyotrophic lateral sclerosis (ALS) is characterised by the progressive degeneration of
upper and lower motor neurons. Besides motor neuron degeneration, ALS is associated …

Loss of appetite is associated with a loss of weight and fat mass in patients with amyotrophic lateral sclerosis

ST Ngo, RPA van Eijk, V Chachay… - … lateral sclerosis and …, 2019 - Taylor & Francis
Objective: Weight loss in amyotrophic lateral sclerosis (ALS) is associated with faster
disease progression and shorter survival. It has different possible causes, including loss of …

Early weight loss in amyotrophic lateral sclerosis: outcome relevance and clinical correlates in a population-based cohort

C Moglia, A Calvo, M Grassano, A Canosa… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objectives To assess the role of body mass index (BMI) and of the rate of weight loss as
prognostic factors in amyotrophic lateral sclerosis (ALS) and to explore the clinical correlates …