Introduction: In view of the conflicting evidence of helper T cell type 1 (Th1) or type 2 (Th2)
pattern of cytokine synthesis in steroid sensitive nephrotic syndrome (SSNS), this study …

Children with steroid sensitive nephrotic syndrome (SSNS) is thought to have dysregulated
type-1/type-2 cytokine network. Interleukin (IL)-18 is a cytokine, which may enhance both …

Background: Several cytokines have a pathological association with idiopathic steroid‐
sensitive nephrotic syndrome (ISSNS) in inducing proteinuria or regulating T cells. Because …

Background Various studies reported a higher incidence of allergic disorders, with an
overreactivity of type 2 helper T-cell (Th2) immune mechanisms, in children with idiopathic …

The cause of childhood nephrotic syndrome (NS) is unknown and whether it responds to
steroid therapy remains unpredictable. In the present study, we measured the Th1/Th2 …

Pro-inflammatory cytokines have been suggested in the pathogenesis of idiopathic
nephrotic syndrome (INS), with conflicting results. This study was performed to identify …

Materials and Methods. Fifty-two children with SSNS (21 with atopic disorders and 31
nonatopics) and 60 healthy children were enrolled in the study. The healthy controls were …

Abstract Background/Aims: Interleukin (IL)-18, a member of the IL-1 cytokine superfamily, is
recognized as an important regulator of immune responses. The aim of our study was to …

Materials and Methods. One hundred children with INS and 30 healthy controls were
studied. Genotyping of TNF-α-G308A single nucleotide polymorphism was done using …

Background: Idiopathic Nephrotic syndrome (INS) is an immune-mediated disease in which
a number of cytokines, including IL-4 and IL-13, have been implicated in the pathogenesis …