The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Candida species are part of the normal flora of humans, but once the immune system of the
host is impaired and they escape from commensal niches, they shift from commensal to …

The molecular composition of the cell wall is critical for the biology and ecology of each
fungal species. Fungal walls are composed of matrix components that are embedded and …

Fungal Cell Wall presents a comprehensive examination of the structure, synthesis, and
growth of the fungal cell wall and explores the reasons for the cell wall's importance to the …

The cross‐linking of polysaccharides to assemble new cell wall in fungi requires
transglycosylation mechanisms by which preexisting glycosidic linkages are broken and …

Deadly infections from opportunistic fungi have risen in frequency, largely because of the at-
risk immunocompromised population created by advances in modern medicine and the …

The fungal cell wall is a dynamic structure that protects the cell from changes in osmotic
pressure and other environmental stresses, while allowing the fungal cell to interact with its …

Highlights•Cell wall composition varies with the morphotype.•The structure of the cell wall is
continuously reshuffled by the changes in environmental conditions and stresses.•Cell wall …

Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …

The high mortality of invasive fungal infections, and the limited number and inefficacy of
antifungals necessitate the development of new agents with novel mechanisms and targets …