In previous studies, we determined that the F-box protein Fbp1, a subunit of the SCF (Fbp1)
E3 ligase in Cryptococcus neoformans, is essential for fungal pathogenesis. Heat-killed …

Cryptococcus neoformans is a fungal pathogen that infects the lungs and then often
disseminates to the central nervous system, causing meningitis. How Cryptococcus is able …

Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …

Cryptococcus neoformans is a human fungal pathogen that often causes lung and brain
infections in immunocompromised patients, with a high fatality rate. Our previous results …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …

Cryptococcus neoformans is a major opportunistic fungal pathogen that causes fatal
meningoencephalitis in immunocompromised individuals and is responsible for a large …

Cryptococcus neoformans is the main etiologic agent of cryptococcal meningitis and causes
a significant number of deadly infections per year. Although it is well appreciated that host …

Tumor necrosis factor alpha (TNF-α) plays a critical role in the control of cryptococcal
infection, and its insufficiency promotes cryptococcal persistence. To explore the therapeutic …

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines
are currently available in humans mainly because opportunistic mycoses generally occur …

Cryptococcus neoformans is an opportunistic fungal pathogen that threatens individuals with
impaired cell-mediated immunity (CMI). Presently, there are no standardized vaccines …