Cryptococcus neoformans is an encapsulated fungus that is a frequent cause of
lifethreatening infections in patients with AIDS. C. neoformans has many similarities with …

Dysfunctional polymorphisms of FcγRIIb, an inhibitory receptor, are associated with
Systemic Lupus Erythaematosus (SLE). Cryptococcosis is an invasive fungal infection in …

In the Damage-response framework of microbial pathogenesis, infectious diseases are one
outcome of a host-microorganism interaction in a susceptible host. In cryptococcal disease …

Alternative macrophage activation is associated with exacerbated disease in murine models
of pulmonary cryptococcosis. The present study evaluated the efficacy of interferon-γ …

Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …

Genetically regulated mechanisms of host defense against Cryptococcus neoformans
infection are not well understood. In this study, pulmonary infection with the moderately …

Background Cryptococcus neoformans causes serious disease in immunocompromised
individuals, leading to over 600,000 deaths per year worldwide. Part of this impact is due to …

Cryptococcus gattii is a fungal pathogen that can cause life-threatening respiratory and
disseminated infections in immune-competent and immune-suppressed individuals …

Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

Cryptococcus neoformans is a fungal pathogen causing life-threatening
meningoencephalitis in susceptible individuals. Fungal vaccine development has been …