Sialoglycans play a vital role in physiology, and aberrant sialoglycan expression is
associated with a broad spectrum of diseases. Since biosynthesis of sialoglycans is only …

Sialic acid is an important component of cell surface glycans, which are responsible for
many vital body functions and should therefore be thoroughly studied to understand their …

The metabolic oligosaccharide engineering (MOE) strategy using unnatural sialic acids has
recently enabled the visualization of the sialome in living systems. However, MOE only …

Abstract Sialosides containing (oligo-) N-acetyllactosamine (LacNAc, Galβ (1, 4) GlcNAc) as
core structure are known to serve as ligands for Siglecs. However, the role of tandem inner …

The siglec family of sialic-acid binding proteins is comprised of 15 human and 9 murine
members that are primarily expressed by white blood cells, which mediate innate and …

Sialic acid sugars that terminate cell‐surface glycans form the ligands for the sialic acid
binding immunoglobulin‐like lectin (Siglec) family, which are immunomodulatory receptors …

Exo-enzymatic glycan labeling strategies have emerged as versatile tools for efficient and
selective installation of terminal glyco-motifs onto live cell surfaces. Through employing …

In nature, almost all cells are covered with a complex array of glycan chain namely sialic
acids or nuraminic acids, a negatively charged nine carbon sugars which is considered for …

Cell‐surface sialic acids are essential in mediating a variety of physiological and
pathological processes. Sialic acid chemistry and biology remain challenging to investigate …

Although the vital roles of structures containing sialic acid in biomolecular recognition are
well documented, limited information is available on how sialic acid structural modifications …