Regulatory T (Treg) cells contribute to immune homeostasis but suppress immune
responses to cancer. Strategies to disrupt Treg cell–mediated cancer immunosuppression …

Squamous cell carcinoma (SCC) is the second commonest type of skin cancer. Moreover,
about 90% of head and neck cancers are SCCs. SCCs develop at a significantly higher rate …

Regulatory T (Treg) cells suppress effective antitumor immunity in tumor-bearing hosts,
thereby becoming promising targets in cancer immunotherapy. Despite the importance of …

We hypothesised that Treg cells preferentially expand/infiltrate inside murine
mesotheliomas. Immunotherapy based on the manipulation of Treg cell populations should …

Background Regulatory T cells (Tregs), are a key class of cell types in the immune system. In
the tumor microenvironment (TME), the presence of Tregs has important implications for …

Regulatory T (Treg) cells, an immunosuppressive subset of CD4+ T cells characterized by
the expression of the master transcription factor forkhead box protein P3 (FOXP3), are a …

Regulatory T cells (Treg cells) maintain host self-tolerance but are a major barrier to effective
cancer immunotherapy. Treg cells subvert beneficial anti-tumor immunity by modulating …

Regulatory T cells (Treg) mediate tolerance towards self‐antigens by suppression of innate
and adaptive immunity. In cancer patients, tumor‐infiltrating FoxP3+ Treg suppress local anti …

Regulatory T (Treg) cells mediate homeostatic peripheral tolerance by suppressing
autoreactive T cells. Failure of host antitumor immunity may be caused by exaggerated …

To obtain a molecular definition of regulatory T (Treg) cell identity, we performed proteomics
and transcriptomics on various populations of human regulatory and conventional CD4+ T …