Renin-angiotensin system and myocardial fibrosis in hypertension: regulation of the myocardial collagen matrix.

CG Brilla, GP Reams, B Maisch, KT Weber - European heart journal, 1993 - europepmc.org
The cardiac interstitium is composed of non-myocyte cells embedded in a highly organized
extracellular matrix containing a three-dimensional collagen network which serves to …

Renin-angiotensin system and myocardial collagen matrix remodeling in hypertensive heart disease: in vivo and in vitro studies on collagen matrix regulation

CG Brilla, B Maisch, KT Weber - The clinical investigator, 1993 - Springer
The interstitial space of the myocardium is composed of nonmyocyte cells and a highly
organized collagen network which serves to maintain the architecture and mechanical …

Renin–angiotensin–aldosterone system and myocardial fibrosis

CG Brilla - Cardiovascular research, 2000 - academic.oup.com
See article by Bishop et al.[26](pages 57–67) in this pacing in dogs, were associated with
activation of RAAS issue. and progressive increase in preload. There, myocardial fibrosis …

Renin-angiotensin system in failing heart

H Kawaguchi, A Kitabatake - Journal of molecular and cellular cardiology, 1995 - Elsevier
Extrahepatic synthesis and localization of angiotensinogen have been described in animals,
thus establishing the tissue, renin-angiotensin system. We examined angiotensinogen …

Renin-angiotensin system and myocardial collagen matrix: modulation of cardiac fibroblast function by angiotensin II type 1 receptor antagonism

CG Brilla, C Scheer, H Rupp - Journal of Hypertension, 1997 - journals.lww.com
Background Left ventricular hypertrophy is an adaptive process to increased loading of the
left ventricle. This condition becomes pathologic with impaired myocardial function if the …

Regulation and role of myocardial collagen matrix remodeling in hypertensive heart disease

RC Funck, A Wilke, H Rupp, CG Brilla - Hypertension and the Heart, 1997 - Springer
In hypertensive heart disease, reactive myocardial fibrosis represents as an excessive
accumulation of fibrillar collagen within the normal connective tissue structures of the …

Collagen network of the myocardium: function, structural remodeling and regulatory mechanisms

KT Weber, Y Sun, SC Tyagi, JPM Cleutjens - Journal of molecular and …, 1994 - Elsevier
A collagen network, composed largely of type I and III fibrillar collagens, is found in the
extracellular space of the myocardium. This network has multiple functions which includes a …

Role of angiotensin II and prostaglandin E2 in regulating cardiac fibroblast collagen turnover

CG Brilla, G Zhou, H Rupp, B Maisch… - The American journal of …, 1995 - Elsevier
In hypertensive heart disease, after myocardial infarction or in congestive heart failure,
myocardial fibrosis presenting as a diffuse perivascular and interstitial accumulation of …

Myocardial collagen matrix remodeling and congestive heart failure.

CG Brilla, H Rupp - Cardiologia (Rome, Italy), 1994 - europepmc.org
In chronic heart failure, the inter-relationship of the renin-angiotensin-aldosterone system
(RAAS) and cardiac growth is of primary clinical interest. In the pressure or volume …

The importance of the renin-angiotensin system in reversal of left ventricular hypertrophy.

B Dahlöf - Journal of hypertension. Supplement: Official Journal of …, 1993 - europepmc.org
The importance of the renin-angiotensin system in reversal of left ventricular hypertrophy. -
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