Identifying virus characteristics associated with the largest public health impacts on human
populations is critical to informing “zoonotic risk” assessments and surveillance strategies …

Substantial global attention is focused on how to reduce the risk of future pandemics.
Reducing this risk requires investment in prevention, preparedness, and response. Although …

Bats are the natural reservoirs of a number of high-impact viral zoonoses. We present a
quantitative analysis to address the hypothesis that bats are unique in their propensity to …

Most emerging and re-emerging infectious diseases stem from viruses that naturally
circulate in non-human vertebrates. When these viruses cross over into humans, they can …

Viruses that originate in bats may be the most notorious emerging zoonoses that spill over
from wildlife into domestic animals and humans. Understanding how these infections filter …

Disease dilution (reduced disease prevalence with increasing biodiversity) has been
described for many different pathogens. Although the mechanisms causing this …

Viruses infect all forms of life and play critical roles as agents of disease, drivers of
biochemical cycles and sources of genetic diversity for their hosts. Our understanding of viral …

For a century, two new viruses per year have spilled from their natural hosts into humans (1).
The MERS, SARS, and 2009 H1N1 epidemics, and the HIV and coronavirus disease 2019 …

Understanding host interactions that lead to pathogen transmission is fundamental to the
prediction and control of epidemics,,,–. Although the majority of transmissions often occurs …

There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …