The hydrophobic proteins SP-B and SP-C are essential for pulmonary surfactant function,
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …

Pattle, who provided some of the initial direct evidence for the presence of pulmonary
surfactant in the lung, was also the first to show surfactant was susceptible to proteases such …

Pulmonary surfactant is a lipoprotein complex that reduces surface tension to prevent
alveolar collapse and contributes to the protection of the respiratory surface from the entry of …

Langmuir isotherms and fluorescence and atomic force microscopy images of synthetic
model lung surfactants were used to determine the influence of palmitic acid and synthetic …

Phospholipids have the major role in pulmonary surfactant concerning its biophysical
function of reducing surface tension at the alveolar air-liquid interface to facilitate respiratory …

Revised Manuscript Received September 2, 1994s abstract: Dynamic cyclic surface
pressure (jr)-area measurements were performed on surfactant proteins SP-B and SP-C in …

Pulmonary surfactant protein SP-C is a 35-residue polypeptide composed of a hydrophobic
transmembrane alpha-helix and a polycationic, palmitoylated-cysteine containing N-terminal …

Pulmonary surfactant, a thin lipid/protein film lining mammalian lungs, functions in vivo to
reduce the work of breathing and to prevent alveolar collapse. Analogues of two …

Pulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial
type II cells into the alveolar space. Its main function is to reduce the surface tension at the …

This study investigates the importance of thioester-linked acyl groups in lung surfactant
protein C (SP-C) in facilitating interactions with phospholipids that yield functionally …