Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis
The core human gut microbiota contributes to the developmental origin of diseases by
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …
modifying metabolic pathways. To evaluate the predominant microbiota as an epigenetic …
Gut microbiota composition is associated with the global DNA methylation pattern in obesity
B Ramos-Molina, L Sánchez-Alcoholado… - Frontiers in …, 2019 - frontiersin.org
Objective: Obesity and obesity-related metabolic diseases are characterized by gut
microbiota and epigenetic alterations. Recent insight has suggested the existence of a …
microbiota and epigenetic alterations. Recent insight has suggested the existence of a …
Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development
Background The interplay of epigenetic processes and the intestinal microbiota may play an
important role in intestinal development and homeostasis. Previous studies have …
important role in intestinal development and homeostasis. Previous studies have …
Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes
W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …
Previously, we have found that OP individuals, despite being normal in weight and BMI …
Influences of the gut microbiota on DNA methylation and histone modification
The gut microbiota is a vast ensemble of microorganisms inhabiting the mammalian
gastrointestinal tract that can impact physiologic and pathologic processes. However, our …
gastrointestinal tract that can impact physiologic and pathologic processes. However, our …
Epigenetic regulation at the interplay between gut microbiota and host metabolism
J Miro-Blanch, O Yanes - Frontiers in genetics, 2019 - frontiersin.org
Gut microbiota communities have coevolved for millions of years in a symbiotic relationship
with their mammalian hosts. Elucidating and understanding the molecular mechanisms by …
with their mammalian hosts. Elucidating and understanding the molecular mechanisms by …
Dissecting the interplay mechanism between epigenetics and gut microbiota: health maintenance and disease prevention
Y Wu, CZ Wang, JY Wan, H Yao, CS Yuan - International Journal of …, 2021 - mdpi.com
The gut microbiota exists throughout the full life cycle of the human body, and it has been
proven to have extensive impacts on health and disease. Accumulating evidence …
proven to have extensive impacts on health and disease. Accumulating evidence …
The epigenetic connection between the gut microbiome in obesity and diabetes
M Sharma, Y Li, ML Stoll, TO Tollefsbol - Frontiers in genetics, 2020 - frontiersin.org
Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …
these diseases over the past few decades. Various environmental factors are associated …
The gut microbiota and their metabolites: potential implications for the host epigenome
M Mischke, T Plösch - Microbiota of the human body: implications in health …, 2016 - Springer
The gut microbiota represents a metabolically active biomass of up to 2 kg in adult humans.
Microbiota-derived molecules significantly contribute to the host metabolism. Large amounts …
Microbiota-derived molecules significantly contribute to the host metabolism. Large amounts …
Gut microbiota as important mediator between diet and DNA methylation and histone modifications in the host
P D'Aquila, L Lynn Carelli, F De Rango, G Passarino… - Nutrients, 2020 - mdpi.com
The human gut microbiota is a complex ecosystem consisting of trillions of microorganisms
that inhabit symbiotically on and in the human intestine. They carry out, through the …
that inhabit symbiotically on and in the human intestine. They carry out, through the …