Alzheimer's disease: a systemic review of substantial therapeutic targets and the leading multi-functional molecules

T Umar, N Hoda - Current Topics in Medicinal Chemistry, 2017 - ingentaconnect.com
Alzheimer's Disease (AD) is a fatal neurodegenerative disorder, having a complex aetiology
with numerous possible drug targets. There are targets that have been known for years …

[HTML][HTML] Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease

T Athar, K Al Balushi, SA Khan - Molecular biology reports, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative old age disease that is complex,
multifactorial, unalterable, and progressive in nature. The currently approved therapy …

[HTML][HTML] Dreaming of a new world where Alzheimer's is a treatable disorder

M Catania, G Giaccone, M Salmona… - Frontiers in aging …, 2019 - frontiersin.org
Alzheimer's disease (AD) is the most common form of dementia. It'sa chronic and
untreatable neurodegenerative disease with irreversible progression and has important …

Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?

A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …

[HTML][HTML] Current therapeutic targets for Alzheimer's disease

A Chaudhary, PK Maurya, BS Yadav, S Singh… - Journal of …, 2018 - jbiomed.com
Alzheimer's disease (AD) is one of the most common multifactorial diseases, including a
range of abnormal cellular/molecular processes occurring in different regions of the brain …

Designing multi-targeted therapeutics for the treatment of Alzheimer's disease

I Erdogan Orhan, F Sezer Senol - Current topics in medicinal …, 2016 - ingentaconnect.com
Due to multi-faceted pathology of AD; no drug can seize the progress of the disease,
whereas only the symptomatic treatment is available at the moment. Several drug classes to …

Current perspectives on pharmacotherapy of Alzheimer's disease

K Chopra, S Misra, A Kuhad - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
Introduction: Alzheimer's disease (AD) is a daunting public health threat that has prompted
the scientific community's ongoing efforts to decipher the underlying disease mechanism …

[HTML][HTML] Treatment of Alzheimer's disease: beyond symptomatic therapies

FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …

Multifaceted Alzheimer's disease: Building a roadmap for advancement of novel therapies

D Kaur, T Behl, A Sehgal, S Singh, N Sharma… - Neurochemical …, 2021 - Springer
Alzheimer's disease (AD) is one of the most prevailing neurodegenerative disorders of
elderly humans associated with cognitive damage. Biochemical, epigenetic, and …

Current status of drug targets and emerging therapeutic strategies in the management of Alzheimer's disease

S Ghosh, S Durgvanshi, S Agarwal… - Current …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease affecting the elderly. AD is
associated with a progressive decline in memory and cognitive abilities, drastic changes in …