[PDF][PDF] Management of Alzheimer's Disease: Role of Existing Therapies, Traditional Medicines and New Treatment Targets.

HO Malve - Indian Journal of Pharmaceutical Sciences, 2017 - researchgate.net
Dementia, a common problem in elderly, is rising worldwide including India. Alzheimer's
disease is the main aetiology for dementia. Currently anticholinesterases, N-methyl-D …

A short perspective on the long road to effective treatments for Alzheimer's disease

DS Reynolds - British Journal of Pharmacology, 2019 - Wiley Online Library
Globally, there are approximately 47 million people living with dementia, and about two
thirds of those have Alzheimer's disease (AD). Age is the single biggest risk factor for the …

Current and emerging pharmacological targets for the treatment of Alzheimer's disease

A Morsy, PC Trippier - Journal of Alzheimer's Disease, 2019 - content.iospress.com
No cure or disease-modifying therapy for Alzheimer's disease (AD) has yet been realized.
However, a multitude of pharmacological targets have been identified for possible …

[PDF][PDF] Pharmacological treatment for Alzheimer's disease: current approaches and future strategies

LY Fan, MJ Chiu - Acta Neurol Taiwan, 2010 - ant-tnsjournal.com
More than a decade after the first approval of the use of acetylcholine esterase inhibitor on
patients with Alzheimer's disease, we still not have a single treatment or combination …

Future directions in the treatment of Alzheimer's disease

R Bullock - Expert Opinion on Investigational Drugs, 2004 - Taylor & Francis
Alzheimer's disease (AD) remains the most common of the neurodegenerative disorders. In
the elderly, it represents the most frequently occurring form of dementia, especially if …

Challenges in the treatment of Alzheimer's disease: recent progress and treatment strategies of pharmaceuticals targeting notable pathological factors

YC Kuo, R Rajesh - Expert review of neurotherapeutics, 2019 - Taylor & Francis
Introduction: Alzheimer's disease (AD), a commonly encountered neurodegenerative
disorder, causes cognitive decline and has a devastating effect on the quality of life. AD …

Multi-target directed drugs as a modern approach for drug design towards Alzheimer's disease: an update

M de Freitas Silva, KST Dias, VS Gontijo… - Current Medicinal …, 2018 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive multifactorial neurodegenerative disorder.
Currently, no effective treatment is available and this is due to multiple factors involved in …

Impact of new drugs for therapeutic intervention in Alzheimer's disease

J Olloquequi, M Ettcheto, A Cano, E Sanchez-López… - 2022 - repositorio.uautonoma.cl
The increases in population ageing and growth are leading to a boosting in the number of
people living with dementia, Alzheimer's disease (AD) being the most common cause. In …

Overview of the alzheimer's disease pathology and potential therapeutic targets

AC Cuello, AC Cuello - Pharmacological Mechanisms in Alzheimer's …, 2007 - Springer
This chapter succinctly summarizes some basic aspects of Alzheimer's disease (AD)
pathology for the nonexpert reader. The objective is to provide an overview for subsequent …

Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease

N Kumar, V Kumar, P Anand, V Kumar… - Bioorganic & Medicinal …, 2022 - Elsevier
Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …