Underlying molecular mechanism and construction of a miRNA-gene network in idiopathic pulmonary fibrosis by bioinformatics

S Zheng, Y Zhang, Y Hou, H Li, J He, H Zhao… - International Journal of …, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease, but its
pathogenesis is still unclear. Bioinformatics methods were used to explore the differentially …

[HTML][HTML] Identification and validation of potential biomarkers and pathways for idiopathic pulmonary fibrosis by comprehensive bioinformatics analysis

W Qian, X Cai, Q Qian, X Zhang - BioMed research …, 2021 - pmc.ncbi.nlm.nih.gov
Objective Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, high-
mortality lung disease, but its pathogenesis is still unclear. Our purpose was to explore …

Molecular pathogenesis involved in human idiopathic pulmonary fibrosis based on an integrated microRNA‑mRNA interaction network

L Wang, W Huang, L Zhang… - Molecular medicine …, 2018 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is considered to be an ailment of the lungs that cannot be
cured, wherein the lung tissues are characterized by increased thickness and stiffness …

Study on Potential Differentially Expressed Genes in Idiopathic Pulmonary Fibrosis by Bioinformatics and Next-Generation Sequencing Data Analysis

M Giriyappagoudar, B Vastrad, R Horakeri, C Vastrad - Biomedicines, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with reduced
quality of life and earlier mortality, but its pathogenesis and key genes are still unclear. In …

Bioinformatic analysis of next-generation sequencing data to identify dysregulated genes in fibroblasts of idiopathic pulmonary fibrosis

CC Sheu, WA Chang, MJ Tsai… - International …, 2019 - spandidos-publications.com
Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease with an increasing global
burden. It is hypothesized that fibroblasts have a number of functions that may affect the …

Using bioinformatics approach identifies key genes and pathways in idiopathic pulmonary fibrosis

Z Xu, L Mo, X Feng, M Huang, L Li - Medicine, 2020 - journals.lww.com
Idiopathic pulmonary fibrosis is a chronic and irreversible respiratory disease with a high
incidence worldwide and no specific treatment. Currently, the etiology and pathogenesis of …

[HTML][HTML] Integrated analysis of the molecular mechanisms in idiopathic pulmonary fibrosis

K Zhu, A Xu, W Xia, P Li, R Han, E Wang… - … Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Rationale: Idiopathic pulmonary fibrosis (IPF) is one of the most aggressive forms of
idiopathic interstitial pneumonia. Some miRNAs may be associated with IPF and may affect …

Analysis of the interaction network of hub miRNAs-hub genes, being involved in idiopathic pulmonary fibers and its emerging role in non-small cell lung cancer

DH Yu, XL Ruan, JY Huang, XP Liu, HL Ma… - Frontiers in …, 2020 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fibrotic interstitial lung disease with lesions confined
to the lungs. To identify meaningful microRNA (miRNA) and gene modules related to the IPF …

[HTML][HTML] Weighted gene coexpression network analysis identifies key genes and pathways associated with idiopathic pulmonary fibrosis

Z Wang, J Zhu, F Chen, L Ma - Medical Science Monitor …, 2019 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis (IPF) is a life-threatening disease with an
unknown etiology. Gene expression microarray data have provided some insights into the …

Integrated bioinformatics analysis for the identification of idiopathic pulmonary fibrosis–related genes and potential therapeutic drugs

Z Zhang, Q Guan, Y Tian, X Shao, P Zhao… - BMC Pulmonary …, 2023 - Springer
Objective The pathogenesis of idiopathic pulmonary fibrosis (IPF) remains unclear. We
sought to identify IPF-related genes that may participate in the pathogenesis and predict …