Sterilizing immunity: understanding COVID-19
I Wahl, H Wardemann - Immunity, 2022 - cell.com
Immune memory develops during primary infections to protect from future exposures to the
same pathogen. Vaccines mimic this response and induce immune memory that protects …
same pathogen. Vaccines mimic this response and induce immune memory that protects …
Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …
central to long-term control of the current pandemic. Despite our rapidly advancing …
Infection and immune memory: variables in robust protection by vaccines against SARS-CoV-2
SARS-CoV-2 is the cause of a recent pandemic that has led to more than 3 million deaths
worldwide. Most individuals are asymptomatic or display mild symptoms, which raises an …
worldwide. Most individuals are asymptomatic or display mild symptoms, which raises an …
Will SARS-CoV-2 infection elicit long-lasting protective or sterilising immunity? Implications for vaccine strategies (2020)
DS Kim, S Rowland-Jones… - Frontiers in …, 2020 - frontiersin.org
In December 2019, an outbreak of a novel coronavirus (SARS-CoV-2) in Wuhan, China
resulted in the current COVID-19 global pandemic. The human immune system has not …
resulted in the current COVID-19 global pandemic. The human immune system has not …
Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …
previous infections. Immunological memory can develop from multiple branches of the …
Old vaccines for new infections: Exploiting innate immunity to control COVID-19 and prevent future pandemics
K Chumakov, MS Avidan, CS Benn… - Proceedings of the …, 2021 - National Acad Sciences
The COVID-19 pandemic triggered an unparalleled pursuit of vaccines to induce specific
adaptive immunity, based on virus-neutralizing antibodies and T cell responses. Although …
adaptive immunity, based on virus-neutralizing antibodies and T cell responses. Although …
SARS-CoV-2 infection and vaccination trigger long-lived B and CD4+ T lymphocytes with implications for booster strategies
BACKGROUND Immunization against SARS-CoV-2, the causative agent of COVID-19,
occurs via natural infection or vaccination. However, it is currently unknown how long …
occurs via natural infection or vaccination. However, it is currently unknown how long …
New insights into human immune memory from SARS‐CoV‐2 infection and vaccination
Since early 2020, the world has been embroiled in an ongoing viral pandemic with SARS‐
CoV‐2 and emerging variants resulting in mass morbidity and an estimated 6 million deaths …
CoV‐2 and emerging variants resulting in mass morbidity and an estimated 6 million deaths …
[HTML][HTML] Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of …
SARS-CoV-2 infection of vaccinated individuals is increasingly common but rarely results in
severe disease, likely due to the enhanced potency and accelerated kinetics of memory …
severe disease, likely due to the enhanced potency and accelerated kinetics of memory …
Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
LB Rodda, PA Morawski, KB Pruner, ML Fahning… - Cell, 2022 - cell.com
Immune memory is tailored by cues that lymphocytes perceive during priming. The severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic created a situation in …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic created a situation in …