[HTML][HTML] Somatostatin analogues for the prevention of pancreatic fistula after open pancreatoduodenectomy: A nationwide analysis

BT Bootsma, VD Plat, T van de Brug, DE Huisman… - Pancreatology, 2022 - Elsevier
Background Somatostatin analogues (SA) are currently used to prevent postoperative
pancreatic fistula (POPF) development. However, its use is controversial. This study …

The use of prophylactic somatostatin therapy following pancreaticoduodenectomy: a meta-analysis of randomised controlled trials

A Adiamah, Z Arif, F Berti, S Singh, N Laskar… - World Journal of …, 2019 - Springer
Background Prophylactic administration of somatostatin analogues (SA) to reduce the
incidence of post-operative pancreatic fistula (POPF) remains contentious. This meta …

Somatostatin analogues and the risk of post-operative pancreatic fistulas after pancreatic resection-A systematic review & meta-analysis

T Li, RT D'Cruz, SY Lim, VG Shelat - Pancreatology, 2020 - Elsevier
Background Post-operative pancreatic fistula (POPF) is a common complication of
pancreatic resection. Somatostatin analogues (SA) have been used as prophylaxis to …

Systematic review and meta-analysis of somatostatin analogues in the prevention of postoperative complication after pancreaticoduodenectomy

K Jin, H Zhou, J Zhang, W Wang, Y Sun, C Ruan… - Digestive …, 2015 - karger.com
Background: The use of somatostatin analogues (SAs) following pancreaticoduodenectomy
(PD) is controversial. Method: Literature databases were searched systematically for …

Do somatostatin-analogues have the same impact on postoperative morbidity and pancreatic fistula in patients after pancreaticoduodenectomy and distal …

S Schorn, T Vogel, IE Demir, E Demir, O Safak… - Pancreatology, 2020 - Elsevier
Objective Postoperative pancreatic fistula/POPF is the most feared complication in
pancreatic surgery. Although several systematic reviews investigated the impact of …

A randomised, multicentre trial of somatostatin to prevent clinically relevant postoperative pancreatic fistula in intermediate-risk patients after …

Z Cao, J Qiu, J Guo, G Xiong, K Jiang, S Zheng… - Journal of …, 2021 - Springer
Background Prophylactic somatostatin to reduce the incidence of clinically relevant
postoperative pancreatic fistula after pancreaticoduodenectomy remains controversial. We …

[HTML][HTML] A phase II trial of lanreotide for the prevention of postoperative pancreatic fistula

VG Pillarisetty, A Abbasi, JO Park, JG Sham - HPB, 2022 - Elsevier
Background Clinically relevant postoperative pancreatic fistula (CR-POPF) is a significant
contributor to morbidity after pancreatectomy. Somatostatin analogues have shown variable …

Somatostatin vs. Octreotide for Prevention of Postoperative Pancreatic Fistula The PREFIPS Randomized Clinical Trial A FRENCH 007–ACHBT Study

S Gaujoux, JM Regimbeau, G Piessen, S Truant… - 2024 - journals.lww.com
Objective: Pharmacological prevention of postoperative pancreatic fistula (POPF) after
pancreatectomy is open to debate. The present study compares clinically significant POPF …

[HTML][HTML] The effect of somatostatin analogues on postoperative outcomes following pancreatic surgery: A meta-analysis

X Han, Z Xu, S Cao, Y Zhao, W Wu - PLoS One, 2017 - journals.plos.org
Background Leakage from the pancreatic stump is a leading cause of morbidity following
pancreatic surgery. It is essential to evaluate the effect of somatostatin analogues (SAs) …

Clinical evaluation of somatostatin use in pancreatic resections: Clinical efficacy or limited benefit?

RJ Anderson, E Dunki-Jacobs, GG Callender… - Surgery, 2013 - Elsevier
Background The benefit of somatostatin for the prevention of pancreatic fistula has been
debated widely in the literature. The aim of this study was to evaluate the efficacy of …